E
Eran Meshorer
Researcher at Hebrew University of Jerusalem
Publications - 135
Citations - 9515
Eran Meshorer is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Chromatin & Embryonic stem cell. The author has an hindex of 40, co-authored 127 publications receiving 8438 citations. Previous affiliations of Eran Meshorer include National Institutes of Health.
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Journal ArticleDOI
Spironolactone inhibits the growth of cancer stem cells by impairing DNA damage response
Ayala Gold,Lital Eini,Malka Nissim-Rafinia,Ruth Viner,Shlomit Ezer,Keren Erez,Nasma Aqaqe,Rotem Hanania,Michael Milyavsky,Eran Meshorer,Michal Goldberg +10 more
TL;DR: It is revealed that spironolactone does not damage the DNA but impairs DSB repair and induces apoptosis in cancer cells and CSCs while sparing healthy cells, and is suggested as an anticancer reagent, toxic to both cancer Cells and, particularly to, C SCs.
BookDOI
The cell biology of stem cells
Eran Meshorer,Kathrin Plath +1 more
TL;DR: Embryonic Stem Cells as a Model to Study Transcriptional Regulation Transcription Factors Governing ESC Pluripotency TranscriptionALRegulatory Network Technologies for Dissecting the Trans transcriptional Regulatory Network.
Journal ArticleDOI
Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation
Raghu Ram Edupuganti,Arigela Harikumar,Yair Aaronson,Alva Biran,Badi Sri Sailaja,Malka Nissim-Rafinia,Gajendra Kumar Azad,Malkiel A. Cohen,Jung Eun Park,Chikdu S. Shivalila,Styliani Markoulaki,Siu Kwan Sze,Rudolf Jaenisch,Eran Meshorer +13 more
TL;DR: This work identifies an important regulator of pluripotency and early differentiation, which is controlled by alternative promoter usage, and photobleaching methods demonstrate SET's role in maintaining a dynamic chromatin state in ESCs.
Journal ArticleDOI
Glioblastoma initiating cells are sensitive to histone demethylase inhibition due to epigenetic deregulation
Jan-Philipp Mallm,Paul Y. Windisch,Alva Biran,Zoltan Gal,Sabrina Schumacher,Rainer Glass,Christel Herold-Mende,Eran Meshorer,Martje Barbus,Karsten Rippe +9 more
TL;DR: This work identifies stem cell‐like chromatin features in human glioblastoma initiating cells and links them to a loss of the repressive histone H3 lysine 9 trimethylation mark, which is crucial for GIC viability.