Eric de La Fortelle

TL;DR: This chapter discusses the maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement (MIR) and multiwavelength anomalous diffraction (MAD) and its extension to probability distributions incorporating anomalousdiffraction effects, as well as measurement error and nonisomorphism.

TL;DR: Crystal structures suggest that the seven Sm proteins could form a closed ring and the snRNAs may be bound in the positively charged central hole.

TL;DR: The HAP1 structure suggests a mechanism for AP site binding which involves the recognition of the deoxyribose moiety in an extra‐helical conformation, rather than a ‘flipped‐out’ base opposite the AP site.

TL;DR: The groove and pocket are the sites of substrate binding and the floor of the pocket is the catalytic center of N-myristoyl transferase, which has a novel α/β fold which shows internal twofold symmetry, which may be a result of gene duplication.

TL;DR: The determination of the crystal structure of a member of the elicitin family may make it possible to separate the activity that causes leaf necrosis from that inducing systemic acquired resistance to pathogens, making it feasible to engineer a non-toxic elicitin that only elicits plant defences.