E
Eric G. Neilson
Researcher at Northwestern University
Publications - 247
Citations - 31746
Eric G. Neilson is an academic researcher from Northwestern University. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 73, co-authored 247 publications receiving 29759 citations. Previous affiliations of Eric G. Neilson include University of Kansas & University of Michigan.
Papers
More filters
Journal ArticleDOI
Epithelial-mesenchymal transition and its implications for fibrosis.
Raghu Kalluri,Eric G. Neilson +1 more
TL;DR: This review highlights recent advances in the process of EMT signaling in health and disease and how it may be attenuated or reversed by selective cytokines and growth factors.
Journal ArticleDOI
Stromal fibroblasts in cancer initiation and progression
TL;DR: It is revealed that fibroblasts have a more profound influence on the development and progression of carcinomas than was previously appreciated and this has important therapeutic implications.
Journal ArticleDOI
Biomarkers for epithelial-mesenchymal transitions
Michael Zeisberg,Eric G. Neilson +1 more
TL;DR: It is believed that context and various changes in plasticity biomarkers can help identify at least three types of EMT and that using a collection of criteria for EMT increases the likelihood that everyone is studying the same phenomenon - namely, the transition of epithelial and endothelial cells to a motile phenotype.
Journal ArticleDOI
Evidence that fibroblasts derive from epithelium during tissue fibrosis
Masayuki Iwano,David Plieth,Theodore M. Danoff,Theodore M. Danoff,Chengsen Xue,Hirokazu Okada,Hirokazu Okada,Eric G. Neilson +7 more
TL;DR: The findings suggest that a substantial number of organ fibroblasts appear through a novel reversal in the direction of epithelial cell fate, which highlights the potential plasticity of differentiated cells in adult tissues under pathologic conditions.
Journal ArticleDOI
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
Elisabeth M. Zeisberg,Oleg Tarnavski,Michael Zeisberg,Adam L. Dorfman,Julie R. McMullen,Erika Gustafsson,Anil Chandraker,Xueli Yuan,William T. Pu,Anita B. Roberts,Eric G. Neilson,Mohamed H. Sayegh,Seigo Izumo,Raghu Kalluri +13 more
TL;DR: It is shown that cardiac fibrosis is associated with the emergence of fibroblasts originating from endothelial cells, suggesting an endothelial-mesenchymal transition (EndMT) similar to events that occur during formation of the atrioventricular cushion in the embryonic heart.