Eric Goemaere

TL;DR: Several lines of evidence suggest that alternative mechanisms-including pharmacokinetic variability, induction of efflux pumps that transport the drug out of cells, and suboptimal drug penetration into tuberculosis lesions-are likely crucial to the pathogenesis of drug-resistant tuberculosis.

TL;DR: A three‐tier monitoring system at country level for pre‐antiretroviral wellness, ART, tuberculosis and mother and child health services can be an efficient approach to ensuring system‐wide harmonization and accurate monitoring of services, including long term retention in care, during the scale‐up of electronic monitoring solutions.

TL;DR: There is much to celebrate at the end of the first decade of South Africa’s public sector antiretroviral therapy (ART) programme, making it the largest ART programme globally and the critical role that donor-funded pilot ART projects have played in establishing the feasibility of public health ART programmes.

TL;DR: It is proposed that the option to remain on lifelong antiretroviral therapy, effectively adopting PMTCT Option B+, be offered to pregnant women following the cessation of breastfeeding, for their own health, following the provision of counselling on associated benefits and risks.

TL;DR: Great progress has been made in the prevention of mother-to-child transmission (PMTCT) of HIV in South Africa in the past ten years, and this is reflected in the achievements of the health services in Khayelitsha.