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Treatment Action Group

NonprofitNew York, New York, United States
About: Treatment Action Group is a nonprofit organization based out in New York, New York, United States. It is known for research contribution in the topics: Tuberculosis & Acquired immunodeficiency syndrome (AIDS). The organization has 27 authors who have published 156 publications receiving 6063 citations.


Papers
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Journal ArticleDOI
TL;DR: It is proposed that the internationally recommended algorithm for the diagnosis of smear-negative pulmonary tuberculosis should be revised to include HIV status, severity of AIDS and tuberculosis, and early use of chest radiography in the decision tree.

532 citations

Journal ArticleDOI
TL;DR: Several lines of evidence suggest that alternative mechanisms-including pharmacokinetic variability, induction of efflux pumps that transport the drug out of cells, and suboptimal drug penetration into tuberculosis lesions-are likely crucial to the pathogenesis of drug-resistant tuberculosis.

461 citations

Journal ArticleDOI
TL;DR: This review synthesizes the state of engagement in HIV care in the United States, focusing on research, practice, and policy considerations, and includes a look to the future in addressing the greatest challenge and opportunity facing the authors' domestic HIV epidemic.
Abstract: The National HIV/AIDS Strategy and the promise of treatment as prevention have garnered considerable attention from the policy, practice, and scientific communities, with the treatment cascade becoming the sentinel image illustrating the domestic human immunodeficiency virus (HIV) epidemic. The cascade depicts prevalence estimates for sequential steps from HIV diagnosis through viral suppression, the most striking of which is that >50% of persons diagnosed with HIV are not in medical care. This heterogeneous group includes individuals not linked to medical care following HIV diagnosis and those entering care who are not retained, requiring reengagement from a range of community settings. This review synthesizes the state of engagement in HIV care in the United States, focusing on research, practice, and policy considerations. Included are conceptual frameworks, a review of health implications, measurement, monitoring, and evidence-based intervention approaches, and a look to the future in addressing the greatest challenge and opportunity facing our domestic HIV epidemic.

456 citations

Journal ArticleDOI
TL;DR: A group of international experts to develop a scientific strategy for research towards an HIV cure summarized the group's strategy in this Perspective.
Abstract: Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a global population of more than 35 million people living with HIV, there is intense interest in developing a cure for HIV infection. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. This Perspective summarizes the group's strategy.

376 citations

Journal ArticleDOI
TL;DR: The number of US residents who have been infected with hepatitis C is unknown but is probably at least 4.6 million, although additional sources of potential underestimation suggest that the true prevalence could well be higher.

371 citations


Authors

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Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20221
20215
202011
20197
201811
201711