E
Eric J. Kremer
Researcher at University of Montpellier
Publications - 150
Citations - 9544
Eric J. Kremer is an academic researcher from University of Montpellier. The author has contributed to research in topics: Viral vector & Adenoviridae. The author has an hindex of 45, co-authored 143 publications receiving 8417 citations. Previous affiliations of Eric J. Kremer include Centre national de la recherche scientifique & Boston Children's Hospital.
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Journal ArticleDOI
Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n.
Eric J. Kremer,M. Pritchard,Michael Lynch,S. Yu,K. Holman,Elizabeth Baker,Stephen T. Warren,David Schlessinger,G. R. Sutherland,Robert I. Richards +9 more
TL;DR: The sequence of a Pst I restriction fragment was determined that demonstrate instability in fragile X syndrome pedigrees and the region of instability was localized to a trinucleotide repeat p(CCG)n as mentioned in this paper.
Journal ArticleDOI
Fragile X genotype characterized by an unstable region of DNA
S. Yu,M. Pritchard,Eric J. Kremer,Michael Lynch,J.K. Nancarrow,Elizabeth Baker,K. Holman,John C. Mulley,Stephen T. Warren,David Schlessinger,G. R. Sutherland,Robert I. Richards +11 more
TL;DR: This probe provides a means with which to analyze fragile X pedigrees and is a diagnostic reagent for the fragile X genotype.
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Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping.
Kevin T. Beier,Elizabeth E. Steinberg,Katherine E. DeLoach,Stanley Xie,Kazunari Miyamichi,Lindsay A. Schwarz,Xiaojing J. Gao,Eric J. Kremer,Robert C. Malenka,Liqun Luo +9 more
TL;DR: The utility of viral-genetic tracing strategies to elucidate the complex neural substrates that underlie motivated behaviors is highlighted, including a previously unappreciated top-down reinforcing circuit from anterior cortex to lateral nucleus accumbens via VTA-DA neurons.
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Viral-genetic tracing of the input–output organization of a central noradrenaline circuit
Lindsay A. Schwarz,Kazunari Miyamichi,Xiaojing J. Gao,Kevin T. Beier,Brandon Weissbourd,Katherine E. DeLoach,Jing Ren,Sandy Ibanes,Robert C. Malenka,Eric J. Kremer,Liqun Luo +10 more
TL;DR: A set of viral-genetic tools to quantitatively analyse the input–output relationship of neural circuits are developed and applied to dissect the LC-NE circuit in mice, finding that LC- NE neurons projecting to diverse output regions receive mostly similar input.
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Canine adenovirus vectors: an alternative for adenovirus-mediated gene transfer.
TL;DR: CAV vectors were replication defective in all cell lines tested, transduced human-derived cells at an efficiency similar to that of a comparable human adenovirus type 5 vector, and are amenable to in vivo use.