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Eric L. Huang
Researcher at Pacific Northwest National Laboratory
Publications - 6
Citations - 445
Eric L. Huang is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Laser capture microdissection & Mutualism (biology). The author has an hindex of 5, co-authored 6 publications receiving 347 citations.
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Journal ArticleDOI
Predicting Species-Resolved Macronutrient Acquisition during Succession in a Model Phototrophic Biofilm Using an Integrated ‘Omics Approach
Stephen R. Lindemann,Stephen R. Lindemann,Jennifer M. Mobberley,Jessica K. Cole,L. M. Markillie,Ronald C. Taylor,Eric L. Huang,William B. Chrisler,H. S. Wiley,Mary S. Lipton,William C. Nelson,James K. Fredrickson,Margaret F. Romine +12 more
TL;DR: Niche partitioning around nitrogen sources may structure the community when organisms directly compete for limited phosphate, and niche complementarity around nitrogen Sources may increase community diversity and productivity in phosphate-limited phototrophic communities.
Journal ArticleDOI
Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples.
Geremy Clair,Paul D. Piehowski,Teodora Nicola,Joseph A. Kitzmiller,Eric L. Huang,Erika M. Zink,Ryan L. Sontag,Daniel J. Orton,Ronald J. Moore,James P. Carson,Richard D. Smith,Jeffrey A. Whitsett,Richard A. Corley,Namasivayam Ambalavanan,Charles Ansong +14 more
TL;DR: This approach for the first time characterized the ontogeny of protein changes during normal lung development in microdissected alveolar tissue containing only 4,000 cells, and revealed seven defined modules of coordinated transcription factor-signaling molecule expression patterns, suggesting a complex network of temporal regulatory control directsnormal lung development with epigenetic regulation fine-tuning pre-natal developmental processes.
Journal ArticleDOI
SNaPP: Simplified Nanoproteomics Platform for Reproducible Global Proteomic Analysis of Nanogram Protein Quantities.
Eric L. Huang,Paul D. Piehowski,Daniel J. Orton,Ronald J. Moore,Wei-Jun Qian,Cameron P. Casey,Xiaofei Sun,Sudhansu K. Dey,Kristin E. Burnum-Johnson,Richard D. Smith +9 more
TL;DR: A system that minimizes sample handling by using online immobilized trypsin digestion and solid phase extraction to create a simple, sensitive, robust, and reproducible platform for the analysis of nanogram-size proteomic samples is presented.
Journal ArticleDOI
The fungal cultivar of leaf-cutter ants produces specific enzymes in response to different plant substrates.
Lily Khadempour,Lily Khadempour,Kristin E. Burnum-Johnson,Erin S. Baker,Carrie D. Nicora,Bobbie-Jo M. Webb-Robertson,Richard A. White,Matthew E. Monroe,Eric L. Huang,Richard D. Smith,Cameron R. Currie,Cameron R. Currie +11 more
TL;DR: Flexible, substrate‐specific enzymatic response of the fungal cultivar allows leaf‐cutter ants to derive energy from a wide range of substrates, which likely contributes to their ability to be dominant generalist herbivores.
Journal ArticleDOI
The fungus gardens of leaf‐cutter ants undergo a distinct physiological transition during biomass degradation
Eric L. Huang,Frank O. Aylward,Young-Mo Kim,Bobbie-Jo M. Webb-Robertson,Carrie D. Nicora,Zeping Hu,Thomas O. Metz,Mary S. Lipton,Richard D. Smith,Cameron R. Currie,Kristin E. Burnum-Johnson +10 more
TL;DR: The results reveal that numerous free amino acids and sugars are depleted throughout the process of biomass degradation, indicating that easily accessible nutrients from plant material are readily consumed by microbes in these ecosystems.