E
Erin M. Wissink
Researcher at Cornell University
Publications - 16
Citations - 585
Erin M. Wissink is an academic researcher from Cornell University. The author has contributed to research in topics: Cytotoxic T cell & Transcription factor. The author has an hindex of 8, co-authored 14 publications receiving 442 citations. Previous affiliations of Erin M. Wissink include University of California, Los Angeles & National Institutes of Health.
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Journal ArticleDOI
Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II
Ramendra N. Saha,Erin M. Wissink,Emma R. Bailey,Meilan Zhao,David C. Fargo,Ji-Yeon Hwang,Kelly R Daigle,J Daniel Fenn,Karen Adelman,Serena M. Dudek +9 more
TL;DR: It is strongly indicated that the rapid induction of neuronal IEGs requires poised Pol II and a role for this mechanism in a wide variety of transcription-dependent processes, including learning and memory is suggested.
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Nascent RNA analyses: tracking transcription and its regulation
TL;DR: This Review provides an overview of different approaches for measuring nascent RNA synthesis and discusses the complementary strengths of these different methods and how they have contributed to a mechanistic understanding of transcription regulation.
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Rapid Proliferation and Differentiation Impairs the Development of Memory CD8+ T Cells in Early Life
Norah L. Smith,Erin M. Wissink,Jocelyn Wang,Jennifer F. Pinello,Miles P. Davenport,Andrew Grimson,Brian D. Rudd +6 more
TL;DR: It is shown that neonatal and adult CD8+ T cells adopted different fates when responding to equal amounts of stimulation in the same host, and that impaired neonatal memory formation was not due to a lack of responsiveness, but instead because neonatal CD8- T cells expanded more rapidly than adult cells and quickly became terminally differentiated.
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Fetal and adult progenitors give rise to unique populations of CD8+ T cells
TL;DR: It is demonstrated that neonatal CD8+ T cells preferentially become short-lived effectors and adult CD8- T cells selectively form long-lived memory cells after infection because they are derived from distinct progenitor cells.
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miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells.
TL;DR: It is shown that in the absence of the microRNA miR-150, CD8+ T cells fail to undergo robust expansion and differentiation into short-lived terminal effector cells in response to primary infection with Listeria monocytogenes or Vaccinia virus.