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Erwin A. Galinski
Researcher at University of Bonn
Publications - 103
Citations - 6695
Erwin A. Galinski is an academic researcher from University of Bonn. The author has contributed to research in topics: Ectoine & Osmoprotectant. The author has an hindex of 43, co-authored 103 publications receiving 6174 citations. Previous affiliations of Erwin A. Galinski include University of Münster & Merck & Co..
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Heterologous ectoine production in Escherichia coli: By-passing the metabolic bottle-neck
TL;DR: Co-expression of the ectoine biosynthesis genes and of the gene of the feedback-resistant aspartate kinase from Corynebacterium glutamicum MH20-22B (lysC) led to markedly increased production of ectoine in E. coli DH5α, resulting in cytoplasmic ectoine concentrations comparable to those reached via ectoine accumulation from the medium.
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Biosynthesis and fate of compatible solutes in extremely halophilic phototrophic eubacteria
Hans G. Trüper,Erwin A. Galinski +1 more
TL;DR: The labelling of trehalose indicates that the Calvin cycle is blocked in the presence of acetate, which indicated the following biosynthesis pathways: glycine, derived from glyoxylate out of the Kornberg cycle, undergoes a three-fold methylation with S-adenosylmethionine as methyl donor.
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Glass-forming property of hydroxyectoine is the cause of its superior function as a desiccation protectant.
TL;DR: It is demonstrated that hydroxyectoine, in contrast to ectoine, is a good glass-forming compound and its accumulation in response to increased salinity and elevated temperature by halophiles such as Halomonas elongata and its successful application in ``anhydrobiotic engineering'' of both enzymes and whole cells.
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Influence of salts and pH on growth and activity of a novel facultatively alkaliphilic, extremely salt-tolerant, obligately chemolithoautotrophic sufur-oxidizing Gammaproteobacterium Thioalkalibacter halophilus gen. nov., sp. nov. from South-Western Siberian soda lakes.
Horia L. Banciu,Dimitry Y. Sorokin,Dimitry Y. Sorokin,Tatyana P. Tourova,Erwin A. Galinski,Maria S. Muntyan,J. Gijs Kuenen,Gerard Muyzer +7 more
TL;DR: Strain ALCO 1 represents an interesting chemolithoautotrophic model organism for comparative investigations of bacterial adaptations to high salinity and pH and is proposed as a new genus and species Thioalkalibacter halophilus gen. sp.
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Isolation and structure determination of a novel compatible solute from the moderately halophilic purple sulfur bacterium Ectothiorhodospira marismortui
Erwin A. Galinski,Aharon Oren +1 more
TL;DR: The relatively high cytoplasmic concentration of this compound observed at all growth conditions suggests that it may serve a vital function as an osmoticum and/or protectant for Ectothiorhodospira marismortui in a saline environment.