E
Erwin Neher
Researcher at Max Planck Society
Publications - 208
Citations - 54453
Erwin Neher is an academic researcher from Max Planck Society. The author has contributed to research in topics: Exocytosis & Calyx of Held. The author has an hindex of 107, co-authored 200 publications receiving 53036 citations. Previous affiliations of Erwin Neher include University of Giessen & Macau University of Science and Technology.
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Journal ArticleDOI
Multiple calcium-dependent processes related to secretion in bovine chromaffin cells
Erwin Neher,Robert S. Zucker +1 more
TL;DR: The caged calcium compound DM-nitrophen is used to investigate the kinetics of calcium-dependent secretion in bovine chromaffin cells and both secretion and movement of vesicles between pools appear to be [Ca2+]i sensitive.
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Linearized Buffered Ca2+ Diffusion in Microdomains and Its Implications for Calculation of [Ca2+] at the Mouth of a Calcium Channel
Mohammad Naraghi,Erwin Neher +1 more
TL;DR: A linear approximation of the combined reaction–diffusion problem is presented, which can be solved explicitly and accounts for an arbitrary number of calcium buffers, either endogenous or added exogenously.
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Conductance Fluctuations and Ionic Pores in Membranes
Erwin Neher,Charles F. Stevens +1 more
TL;DR: This review describes recent progress in the analysis of statistical fluctuations in membrane conductance and stresses the relation between the kinetics of channel gating as revealed by fluctuation analysis and the relaxation kinetics measured in standard voltage clamp experiments.
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Capacitance measurements reveal stepwise fusion events in degranulating mast cells.
TL;DR: The results show that degranulation occurs spontaneously and reproducibly if the GTP analogue, GTP-γ-S, and Mg-ATP are present in the pipette filling solution and that guanine nucleotide regulatory proteins are involved in the control of this process.
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Regulation of calcium influx by second messengers in rat mast cells
TL;DR: In rat peritoneal mast cells a cAMP- and Ca-activated chloride current can interact with IP3-dependent calcium influx to provide the sustained elevation of intracellular Ca concentration following transient IP2-induced release of calcium from intrACEllular stores.