E
Erwin Neher
Researcher at Max Planck Society
Publications - 208
Citations - 54453
Erwin Neher is an academic researcher from Max Planck Society. The author has contributed to research in topics: Exocytosis & Calyx of Held. The author has an hindex of 107, co-authored 200 publications receiving 53036 citations. Previous affiliations of Erwin Neher include University of Giessen & Macau University of Science and Technology.
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Chloride conductance activated by external agonists and internal messengers in rat peritoneal mast cells.
TL;DR: The Cl‐ current was reduced by 4,4'‐diisothiocyano‐2,2'‐stilbenedisulphonate (DIDS), and during DIDS blockade, the variance of the current increased, suggesting that DIDS enters and blocks the open channel.
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Ionic specificity of the gramicidin channel and the thallous ion
TL;DR: The thallous ion was found to interact very specifically with gramicidin channels in black lipid membranes, and blocks Na+ currents at concentrations which are two orders of magnitude lower than the Na+ concentrations.
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The patch-clamp technique in the study of secretion.
Reinhold Penner,Erwin Neher +1 more
TL;DR: It was only recently that the technique of time-resolved membrane capacitance measurement has provided a more detailed insight into mechanistic aspects of exocytosis, both in terms of the fusion event and the steps involved in stimulus-secretion coupling.
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Intracellular calcium release mediated by two muscarinic receptor subtypes
TL;DR: Four subtypes of muscarinic acetylcholine receptor (mAChR) were stably expressed in neuroblastoma‐glioma hybrid cells (NG108‐15) and it is shown that stimulation of mAChR I and mA ChR III readily leads to release of calcium from intracellular stores and to associated conductance changes.
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Effects of hydrostatic pressure on membrane processes. Sodium channels, calcium channels, and exocytosis.
TL;DR: The process of exocytosis is the most likely site at which hydrostatic pressure can act to produce nervous disorders, and pressure can be a useful tool in the investigation of other cellular responses, since it was able to separate different steps occurring during exocyTosis owing to their different activation volumes.