E
Erwin Neher
Researcher at Max Planck Society
Publications - 208
Citations - 54453
Erwin Neher is an academic researcher from Max Planck Society. The author has contributed to research in topics: Exocytosis & Calyx of Held. The author has an hindex of 107, co-authored 200 publications receiving 53036 citations. Previous affiliations of Erwin Neher include University of Giessen & Macau University of Science and Technology.
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Journal ArticleDOI
Molecular biology meets microelectronics.
TL;DR: A cell and a chip are separated by an electrolyte layer, the specific conductance of which is relatively high, and only intracellular potential gradients and/or gradients in channel density lead to net cur- rents in the cleft 6.
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Washout phenomena in dialyzed mast cells allow discrimination of different steps in stimulus-secretion coupling
TL;DR: The fast “washout” phenomenon of exocytosis could be overcome by supplementing the pipette filling solution with guanosinetriphosphate (GTP), indicating a major role for GTP-binding proteins in secretion.
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The timing of phasic transmitter release is Ca2+-dependent and lacks a direct influence of presynaptic membrane potential
TL;DR: The amplitude and time course of the [Ca2+]i signal at the sites of vesicle fusion controls the timing and the amount of transmitter release, both under conditions of brief periods of Ca2+ influx, as well as during step-like elevations of [Ca1-i produced by Ca2- uncaging.
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Veratridine-induced oscillations of cytosolic calcium and membrane potential in bovine chromaffin cells.
TL;DR: Bovine chromaffin cells have the machinery required for [Ca2+]i oscillations even though the more physiological stimulus tested here (high K+, field electrical stimulation, nicotinic or muscarinic agonists) produced mainly non‐oscillatory responses.
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The Dionaea muscipula ammonium channel DmAMT1 provides NH4+ uptake associated with Venus flytrap's prey digestion.
Sönke Scherzer,Sönke Scherzer,Elzbieta Krol,Elzbieta Krol,Ines Kreuzer,Jörg Kruse,Franziska Karl,Martin von Rüden,María Escalante-Pérez,Thomas Müller,Heinz Rennenberg,Khaled A. S. Al-Rasheid,Erwin Neher,Rainer Hedrich +13 more
TL;DR: It is suggested that regulation of glandular DmAMT1 and membrane potential readjustments of the endocrine cells provide for effective adaptation to varying, prey-derived ammonium sources.