Esin B. Sozer

TL;DR: The results set the stage for the development of future multi-staged DLA devices composed of integrated on-chip systems, and would substantially reduce the size and cost of a future collider on the multi-TeV (1012 eV) scale.

TL;DR: Calcium electroporation dose-dependently reduced cell survival and intracellular ATP and could be a novel cancer treatment and possibly lowering the applied electric field in future trials.

TL;DR: absolute values for the uptake of YO-PRO-1, a small-molecule fluorescent indicator of membrane integrity, into cells after a single electric pulse lasting only 6 ns are reported, challenging the “drift and diffusion through a pore” model for the electroporative transfer of small molecules into cells and point to the necessity for a more complex model.

TL;DR: This work shows how temporal summation when pulses are compressed into high-rate bursts is a universal and efficient way to lower excitation thresholds and facilitate electroporation.

TL;DR: A quantitative analysis of the post-permeabilization transport of three small molecules commonly used in electroporation research — YO-PRO-1, propidium, and calcein — after exposure of cells to minimally perturbing, 6 ns electric pulses reveals a component of the mechanism of Electroporation that is customarily taken into account only for the time during electric pulse delivery.