E
Ester Sánchez-Tilló
Researcher at University of Barcelona
Publications - 30
Citations - 2731
Ester Sánchez-Tilló is an academic researcher from University of Barcelona. The author has contributed to research in topics: Macrophage proliferation & MAPK/ERK pathway. The author has an hindex of 23, co-authored 30 publications receiving 2447 citations.
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Journal ArticleDOI
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.
Ester Sánchez-Tilló,Yongqing Liu,Oriol de Barrios,Laura Siles,Lucia Fanlo,Miriam Cuatrecasas,Douglas S. Darling,Douglas C. Dean,Antoni Castells,Antonio Postigo +9 more
TL;DR: EMT-ATFs have been shown to cooperate in oncogenic transformation, regulate cancer cell stemness, override safeguard programs against cancer like apoptosis and senescence, determine resistance to chemotherapy and promote tumor angiogenesis.
Journal ArticleDOI
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.
Ester Sánchez-Tilló,A Lázaro,R Torrent,Miriam Cuatrecasas,Eva C. Vaquero,Antoni Castells,Pablo Engel,Antonio Postigo +7 more
TL;DR: ZEB1/BRG1 is identified as a new transcriptional mechanism regulating E-cadherin expression and epithelial-to-mesenchymal transdifferentiation that may be involved during the initial stages of tumor invasion.
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β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
Ester Sánchez-Tilló,Oriol de Barrios,Laura Siles,Miriam Cuatrecasas,Antoni Castells,Antonio Postigo +5 more
TL;DR: It is shown here that ZEB1 is expressed by epithelial cells in intestinal tumors from human patients (familial adenomatous polyposis) and mouse models (APCMin/+) with germline mutations of APC that result in nuclear accumulation of β-catenin.
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Differential voltage-dependent K+ channel responses during proliferation and activation in macrophages
Rubén Vicente,Artur Escalada,Mireia Coma,Gemma Fuster,Ester Sánchez-Tilló,Carmen López-Iglesias,Concepció Soler,Carles Solsona,Antonio Celada,Antonio Felipe +9 more
TL;DR: The results demonstrate that the differential regulation of VDPC is crucial in intracellular signals determining the specific macrophage response.
Journal ArticleDOI
Homogeneous conjugation of peptides onto gold nanoparticles enhances macrophage response.
Neus G. Bastús,Ester Sánchez-Tilló,Silvia Pujals,Consol Farrera,Carmen Caja López,Ernest Giralt,Antonio Celada,Jorge Lloberas,Víctor F. Puntes +8 more
TL;DR: The basic requirements involved in medical nanoparticle conjugate design to either activate the immune system or hide from it in order to reach their targets before being removed by phagocytes are illustrated.