Eugene F. Douglass

TL;DR: This work has the potential to render complex three-component systems--which have previously been characterized as "analytically intractable"--readily comprehensible to theoreticians and experimentalists alike.

TL;DR: It is shown that MBo is selective for MGO over other biologically relevant dicarbonyls and is suitable for detecting MGO in complex environments, including that of living cells, and its utility in estimating plasma concentrations of MGO is demonstrated.

TL;DR: Head-to-head comparisons of three chemically simple antigens, which are known ligands for endogenous antibodies, reveal rhamnose to be the most efficacious of the synthetic antigen examined.

TL;DR: A novel class of molecules of intermediate size, which possess both the targeting and effector functions of antibodies, which bind simultaneously to prostate-specific membrane antigen and Fc gamma receptor I, thus eliciting highly selective cancer cell phagocytosis are reported.

TL;DR: Computational analysis provides evidence that azaindole- and indole-based attachment inhibitors bind gp120 at an accessory hydrophobic pocket beneath the CD4-binding site and can also adopt multiple unique binding modes in interacting with gp120.