E
Evan H. Phillips
Researcher at Purdue University
Publications - 35
Citations - 1361
Evan H. Phillips is an academic researcher from Purdue University. The author has contributed to research in topics: Angiotensin II & Medicine. The author has an hindex of 15, co-authored 30 publications receiving 1100 citations. Previous affiliations of Evan H. Phillips include Kettering University & Duke Energy.
Papers
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Journal ArticleDOI
Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe
Evan H. Phillips,Oula Penate-Medina,Pat Zanzonico,Richard D. Carvajal,Pauliah Mohan,Yunpeng Ye,John L. Humm,Mithat Gonen,Hovanes Kalaigian,Heiko Schöder,H. William Strauss,Steven M. Larson,Ulrich Wiesner,Michelle S. Bradbury +13 more
TL;DR: The authors found that the nanoparticles were not toxic in a small group of five patients with metastatic melanoma and that the particles were excreted intact via the kidneys and bladder, suggesting safe use of these particles in human cancer diagnostics.
Journal ArticleDOI
Clinically-translated silica nanoparticles as dual-modality cancer-targeted probes for image-guided surgery and interventions
Michelle S. Bradbury,Evan H. Phillips,Pablo H. Montero,Sarah M. Cheal,Hilda Stambuk,Jeremy C. Durack,Constantinos T. Sofocleous,Richard J. C. Meester,Ulrich Wiesner,Snehal G. Patel +9 more
TL;DR: A clinically-translated, integrin-targeting platform for use with both PET and optical imaging that meets a number of key design criteria for improving SLN tissue localization and retention, target-to-background ratios, and clearance from the site of injection and the body is described.
Journal ArticleDOI
Bond-selective photoacoustic imaging by converting molecular vibration into acoustic waves
TL;DR: This review provides an overview of the recent advances made in vibration-based photoacoustic imaging and various biomedical applications enabled by this new technology.
Journal ArticleDOI
Cancer-Targeting Ultrasmall Silica Nanoparticles for Clinical Translation: Physicochemical Structure and Biological Property Correlations
Feng Chen,Kai Ma,Miriam Benezra,Li Zhang,Sarah M. Cheal,Evan H. Phillips,Barney Yoo,Mohan Pauliah,Michael Overholtzer,Pat Zanzonico,Sonia Sequeira,Mithat Gonen,Thomas P. Quinn,Ulrich Wiesner,Michelle S. Bradbury +14 more
TL;DR: The synthesis, characterization, and long-term stability of ultrasmall (<10 nm diameter) dual-modality and integrintargeting silica nanoparticles and the extent to which their surface ligand density differentially modulates key in vitro and in vivo biological activities in melanoma models are reported on.
Journal ArticleDOI
Morphological and Biomechanical Differences in the Elastase and AngII apoE(-/-) Rodent Models of Abdominal Aortic Aneurysms.
Evan H. Phillips,Alexa A Yrineo,Hilary D Schroeder,Katherine E Wilson,Ji-Xin Cheng,Craig J. Goergen +5 more
TL;DR: Evidence is provided from in vivo ultrasound studies of the temporal changes occurring in biomechanical parameters and macromolecules of the aortic wall in each preclinical models of the disease to investigate mechanisms of disease progression or evaluate potential AAA treatments.