J
Ji-Xin Cheng
Researcher at Boston University
Publications - 436
Citations - 27591
Ji-Xin Cheng is an academic researcher from Boston University. The author has contributed to research in topics: Raman scattering & Microscopy. The author has an hindex of 78, co-authored 422 publications receiving 23398 citations. Previous affiliations of Ji-Xin Cheng include RMIT University & Hong Kong University of Science and Technology.
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Journal ArticleDOI
In vitro and in vivo two-photon luminescence imaging of single gold nanorods
Haifeng Wang,Terry B. Huff,Daniel A. Zweifel,Wei He,Philip S. Low,Alexander Wei,Ji-Xin Cheng +6 more
TL;DR: Gold nanorods excited at 830 nm on a far-field laser-scanning microscope produced strong two-photon luminescence (TPL) intensities, with a cos(4) dependence on the incident polarization.
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Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness
Shuhua Yue,Junjie Li,Seung Young Lee,Hyeon Jeong Lee,Tian Shao,Bing Song,Liang Cheng,Timothy A. Masterson,Xiaoqi Liu,Timothy L. Ratliff,Ji-Xin Cheng +10 more
TL;DR: Biochemical study showed that cholesteryl ester accumulation was a consequence of loss of tumor suppressor PTEN and subsequent activation of PI3K/AKT pathway in prostate cancer cells, and open opportunities for diagnosing and treating prostate cancer by targeting the altered cholesterol metabolism.
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Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
Ji-Xin Cheng,X. Sunney Xie +1 more
TL;DR: The transition from spectroscopy to spectroscopic imaging of living systems, which allows the spectrum of biomolecules to act as natural contrast, is opening new opportunities to reveal cellular machinery and to enable molecule-based diagnosis of human diseases with biomarker sensitivity.
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Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets
Florian Wilfling,Huajin Wang,Joel T. Haas,Natalie Krahmer,Travis J. Gould,Aki Uchida,Ji-Xin Cheng,Morven Graham,Romain Christiano,Florian Fröhlich,Xinran Liu,Kimberly K. Buhman,Rosalind A. Coleman,Joerg Bewersdorf,Robert V. Farese,Tobias C. Walther +15 more
TL;DR: The results explain how TG synthesis is coupled with LD growth and identify two distinct LD subpopulations based on their capacity for localized TG synthesis.
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Gold Nanorods Mediate Tumor Cell Death by Compromising Membrane Integrity
TL;DR: Light-activated therapies can be used to eradicate diseased cells and tissues in a noninvasive manner by employing exogenous agents with large absorption cross sections, confining damage to areas of interest with minimal collateral effects.