F
F. Van Leuven
Researcher at Katholieke Universiteit Leuven
Publications - 105
Citations - 5923
F. Van Leuven is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Peptide sequence & Amyloid precursor protein. The author has an hindex of 42, co-authored 105 publications receiving 5774 citations. Previous affiliations of F. Van Leuven include Catholic University of Leuven.
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Journal ArticleDOI
Isolation, characterization, molecular cloning and molecular modelling of two lectins of different specificities from bluebell (Scilla campanulata) bulbs.
L.M. Wright,E. J. M. Van Damme,Annick Barre,Anthony K. Allen,F. Van Leuven,Colin D. Reynolds,Pierre Rougé,Willy J. Peumans +7 more
TL;DR: X-ray crystallographic analysis and molecular modelling studies have demonstrated close relationships in sequence and structure between these lectins and other monocot mannose-binding lectins.
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Molecular characterization of the murinoglobulins
TL;DR: Proteinase inhibitors of the alpha 2-macroglobulin (alpha 2M) type, although well characterized in vitro, still evade a precise description of their actual role in vivo, so at the molecular level all the members of this proteinase inhibitor family in the mouse are analyzed.
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Qualitative and quantitative study of the growth and cell surface properties of Huntington's disease fibroblasts and age-matched controls. Lack of significant differences.
Jj. Cassiman,J. Verlinden,Robert Vlietinck,J Bellemans,F. Van Leuven,J. Deroover,F Baro,H. Van den Berghe +7 more
TL;DR: Different growth and cell surface properties of cells grown from skin biopsy samples from 25 Huntington's chorea patients, 22 at risk patients, and agematched controls were examined in a blind study as discussed by the authors.
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Transgenic mouse models for Alzheimer's disease: the role of GSK-3β in combined amyloid and tau-pathology
TL;DR: The authors in this paper showed that GSK-3β is the missing link between amyloid and tau-pathology, and position GSK3β as prominent player in the pathogenesis in AD.
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Structure of the gene (LRP1) coding for the human alpha 2-macroglobulin receptor lipoprotein receptor-related protein.
F. Van Leuven,L Stas,Carl Hilliker,K. Lorent,Lieve Umans,Lutgarde Serneels,Lut Overbergh,Sophie Torrekens,Diederik Moechars,B. De Strooper,H. Van den Berghe +10 more
TL;DR: The cloning of the entire human gene (LRP1) coding for A2MR/LRP is reported here, and a complex repetitive sequence posed a cloning problem since it was not retrieved from any genomic library screened.