F
F. Van Leuven
Researcher at Katholieke Universiteit Leuven
Publications - 105
Citations - 5923
F. Van Leuven is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Peptide sequence & Amyloid precursor protein. The author has an hindex of 42, co-authored 105 publications receiving 5774 citations. Previous affiliations of F. Van Leuven include Catholic University of Leuven.
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Journal Article
Polymorphous endocytotic organelles in the receptor-mediated endocytosis of gold-labelled alpha 2-macroglobulin complexes by human fibroblasts
B. Van der Schueren,D. Gasser,Peter Marynen,F. Van Leuven,G. David,J J Cassiman,H. Van den Berghe +6 more
TL;DR: The receptor-mediated endocytosis of gold-labelled alpha 2-macroglobulin complexes with trypsin or methylamine was studied by electron microscopy in human skin fibroblasts and numerous intercommunications were particularly obvious between the tubulovesicular structures, the larger vesicles and the multivesicular bodies (MVB).
Journal ArticleDOI
Absence of specific binding of receptor-mediated endocytosis, and of secretion of alpha-2-macroglobulin by cultured endothelial cells.
TL;DR: The production of alpha 2M by human endothelial cells must, therefore, be lower than 3 ng/10(6) cells/48 h, the lower limit of the assay.
Journal ArticleDOI
A 68-kD Antigen, Which Is Probably an N-Terminal Fragment of the VLA-5 α5-Subunit, Is Specific for Differentiating Keratinocytes
B. De Strooper,Rong Rong Wu,Martine Jaspers,B. Van der Schueren,Sylvie Vekemans,Geert Carmeliet,F. Van Leuven,J. J. Van Den Oord,J J Cassiman +8 more
TL;DR: It is suggested that the 68-kD protein is an amino-terminal degradation product of the alpha 5-subunit of the VLA-5 integrin subunit, which provides a new and interesting marker of differentiating keratinocytes.
Journal ArticleDOI
P4-279: Target specificity of nanobodies™ directed against amyloid peptides
Tom Van Dooren,Pascal Merchiers,Peter Borghgraef,Ilse Dewachter,I. Van der Auwera,Stefaan Wera,Marc Lauwereys,B. Roland,Abedelnasser Abulrob,Danica Stanimirovic,Hennie R. Hoogenboom,H. de Haard,F. Van Leuven +12 more