F
F. Van Leuven
Researcher at Katholieke Universiteit Leuven
Publications - 105
Citations - 5923
F. Van Leuven is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Peptide sequence & Amyloid precursor protein. The author has an hindex of 42, co-authored 105 publications receiving 5774 citations. Previous affiliations of F. Van Leuven include Catholic University of Leuven.
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Journal ArticleDOI
Cloning and characterization of the lectin cDNA clones from onion, shallot and leek
E. J. M. Van Damme,Koen Smeets,I. Engelborghs,H. Aelbers,Jan Balzarini,Arpad Pusztai,F. Van Leuven,Irwin J. Goldstein,Willy J. Peumans +8 more
TL;DR: Southern blot analysis of genomic DNA has shown that the onion, shallot and leek lectins are most probably encoded by a family of closely related genes which is in good agreement with the sequence heterogeneity found between different lectin cDNA clones of one species.
Journal ArticleDOI
A gene encoding a hevein-like protein from elderberry fruits is homologous to PR-4 and class V chitinase genes.
E. J. M. Van Damme,Diana Charels,Shibendu Shekhar Roy,K. Tierens,Annick Barre,José C. Martins,Pierre Rougé,F. Van Leuven,M.P. Does,Wj Peumans +9 more
TL;DR: In this article, the authors isolated a chitin-like protein from mature elderberry fruits and compared the N-terminal domain of this protein with the Nterminal domains of a PR-4 (pathogenesis-related) protein, whereas the C terminus is most closely related to that of class V chitins.
Journal ArticleDOI
Purification and structural analysis of an abundant thaumatin-like protein from ripe banana fruit.
Annick Barre,Willy J. Peumans,Laurence Menu-Bouaouiche,E. J. M. Van Damme,Gregory D. May,A. F. Herrera,F. Van Leuven,Pierre Rougé +7 more
TL;DR: It is demonstrated for the first time that fruit-specific (abundant) TLPs are not confined to dicots but occur also in fruits of monocot species.
Journal ArticleDOI
Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB
Kim Serdons,T. Verduyckt,Dominique Vanderghinste,Jan Cleynhens,Peter Borghgraef,Peter Vermaelen,C Terwinghe,F. Van Leuven,K. Van Laere,Hank F. Kung,Guy Bormans,Alfons Verbruggen +11 more
TL;DR: The new (18)F-lab labelled 2-phenylbenzothiazole showed excellent preclinical characteristics comparable with those of the (11)C-labelled PIB, which has known affinity for amyloid beta and promising characteristics as tracer for in vivo visualisation of amyloids deposits in patients suffering from Alzheimer's disease.
Journal ArticleDOI
Alpha-2 macroglobulin controls trophoblast positioning in mouse implantation sites.
TL;DR: Analysis of implantation sites in MAM(-/-)/MUG-1(-/-)mice during pregnancy demonstrates that alpha 2M, and thereby proteinases and/or cytokines whose bio-availability is regulated by alpha 2m, exert significant decidual regulation on trophoblast invasion.