F
F. van Rhee
Researcher at University of Arkansas for Medical Sciences
Publications - 55
Citations - 1893
F. van Rhee is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Transplantation & Multiple myeloma. The author has an hindex of 21, co-authored 55 publications receiving 1630 citations. Previous affiliations of F. van Rhee include University of South Carolina & Memorial Hospital of South Bend.
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Journal ArticleDOI
Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
Leo Rasche,Shweta S. Chavan,Owen W. Stephens,Purvi Patel,Ruslana Tytarenko,Cody Ashby,Michael A Bauer,Caleb K. Stein,Shayu Deshpande,Christopher P. Wardell,Timea Buzder,Gabor Molnar,Maurizio Zangari,F. van Rhee,Sharmilan Thanendrarajan,Carolina Schinke,Joshua Epstein,Faith E. Davies,Brian A Walker,Tobias Meissner,Bart Barlogie,Gareth J. Morgan,Niels Weinhold +22 more
TL;DR: It is suggested that multi-region investigations are critical to understanding intra-patient heterogeneity and the evolutionary processes in multiple myeloma, and the extent of spatial heterogeneity is positively associated with the size of biopsied focal lesions consistent with regional outgrowth of advanced clones.
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VTD combination therapy with bortezomib–thalidomide–dexamethasone is highly effective in advanced and refractory multiple myeloma
Mauricio Pineda-Roman,Maurizio Zangari,F. van Rhee,Elias Anaissie,Jackie Szymonifka,Antje Hoering,Nathan Petty,John Crowley,John D. Shaughnessy,Joshua Epstein,Bart Barlogie +10 more
TL;DR: Both OS and EFS were significantly longer in the absence of prior T exposure and when at least MR status was attained, a finding since reported for a VTD-incorporating tandem transplant trial (Total Therapy 3) for untreated patients with myeloma.
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Dialysis-dependent renal failure in patients with myeloma can be reversed by high-dose myeloablative therapy and autotransplant
Choon Kee Lee,Maurizio Zangari,Bart Barlogie,A. Fassas,F. van Rhee,Raymond Thertulien,Giampaolo Talamo,Firas Muwalla,Elias Anaissie,Klaus Hollmig,Guido Tricot +10 more
TL;DR: The data suggest that significant renal failure can be reversible and AT should be considered early in the disease course, and the role of high-dose melphalan and autologous transplant in reversing dialysis-dependent renal failure is evaluated.
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Iron overload is a major risk factor for severe infection after autologous stem cell transplantation: a study of 367 myeloma patients.
Marisa H. Miceli,Li Dong,Monica Grazziutti,A. Fassas,Raymond Thertulien,F. van Rhee,Bart Barlogie,Elias Anaissie +7 more
TL;DR: Increased pre-transplant BMIS and smoking are significant predictors of severe infection after myeloablative chemotherapy followed by ASCT in myeloma patients.
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Bone marrow transplantation from partially HLA-mismatched family donors for acute leukemia : Single-center experience of 201 patients
Jayesh Mehta,Seema Singhal,Adrian P. Gee,K. Y. Chiang,K. Godder,F. van Rhee,S. DeRienzo,W. O'Neal,Lawrence S. Lamb,Henslee-Downey Pj +9 more
TL;DR: It is concluded that PMRD BMT is a potential treatment option for patients with high-risk acute leukemia who require an alternative donor transplant and fall into a group with a reasonable expected outcome.