F
Fabienne Escande
Researcher at university of lille
Publications - 76
Citations - 3206
Fabienne Escande is an academic researcher from university of lille. The author has contributed to research in topics: Medicine & Ectrodactyly. The author has an hindex of 24, co-authored 68 publications receiving 2601 citations. Previous affiliations of Fabienne Escande include Lille University of Science and Technology & French Institute of Health and Medical Research.
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Journal ArticleDOI
Routine molecular profiling of patients with advanced non-small-cell lung cancer: results of a 1-year nationwide programme of the French Cooperative Thoracic Intergroup (IFCT)
Fabrice Barlesi,Julien Mazieres,Jean-Philippe Merlio,Didier Debieuvre,Jean Mosser,Hervé Lena,L'Houcine Ouafik,Benjamin Besse,Isabelle Rouquette,Virginie Westeel,Fabienne Escande,Isabelle Monnet,Antoinette Lemoine,Remi Veillon,Hélène Blons,Clarisse Audigier-Valette,Pierre-Paul Bringuier,R. Lamy,Michèle Beau-Faller,Jean-Louis Pujol,Jean-Christophe Sabourin,Frédérique Penault-Llorca,Marc G. Denis,Sylvie Lantuejoul,Franck Morin,Quân Tran,P. Missy,Alexandra Langlais,Bernard Milleron,Jacques Cadranel,Jean-Charles Soria,Gérard Zalcman +31 more
TL;DR: The frequency of genetic alterations, acceptable turnaround times in obtaining analysis results, and the clinical advantage provided by detection of a genetic alteration suggest that this nationwide molecular profiling of patients with advanced NSCLC provides a clinical benefit.
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Structural organization and classification of the human mucin genes.
TL;DR: The study of the mucins structure as well as the relationship between structure and function show that mucins also possess other important functions, such as growth, direct implication in the fetal development, the epithelial renewal and differentiation,The epithelial integrity, carcinogenesis, and metastasis.
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Rare EGFR exon 18 and exon 20 mutations in non-small-cell lung cancer on 10 117 patients: a multicentre observational study by the French ERMETIC-IFCT network
Michèle Beau-Faller,Nathalie Prim,A.-M. Ruppert,Isabelle Nanni-Metellus,Roger Lacave,Ludovic Lacroix,Fabienne Escande,Sarab Lizard,Jean-Luc Prétet,Isabelle Rouquette,P. de Cremoux,Jérôme Solassol,F. De Fraipont,Ivan Bièche,Anne Cayre,E. Favre-Guillevin,Pascale Tomasini,Marie Wislez,Benjamin Besse,Michèle Legrain,Anne-Claire Voegeli,Laurence Baudrin,Franck Morin,Gérard Zalcman,Elisabeth Quoix,Hélène Blons,Jacques Cadranel +26 more
TL;DR: Rare EGfr-mutated NSCLCs are heterogeneous, with resistance of distal exon 20 insertions and better sensitivity of exon 18 or complex mutations to EGFR-TKIs, probably requiring individual assessment.
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CDKN2A homozygous deletion is a strong adverse prognosis factor in diffuse malignant IDH-mutant gliomas.
Romain Appay,Caroline Dehais,Claude-Alain Maurage,Agusti Alentorn,Catherine Carpentier,Carole Colin,François Ducray,Fabienne Escande,Ahmed Idbaih,Aurélie Kamoun,Yannick Marie,Karima Mokhtari,Emeline Tabouret,Nesrine Trabelsi,Emmanuelle Uro-Coste,Jean-Yves Delattre,Jean-Yves Delattre,Dominique Figarella-Branger +17 more
TL;DR: This study pointed out the utmost relevance of CDKN2A homozygous deletion as an adverse prognostic factor in the 2 broad categories of IDH-mutant gliomas stratified on 1p/19q codeletion and suggests that the grading of these tumors should be refined.
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Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins
Nicolas Moniaux,Fabienne Escande,Surinder K. Batra,Nicole Porchet,Anne Laine,Jean-Pierre Aubert +5 more
TL;DR: It is suspected that the MUC4 proteins may be implicated in the integrity and renewal of the epithelium, and cloned and characterized unique M UC4 cDNA sequences that differ from the originally published sequence.