F
Fang Ji
Researcher at National University of Singapore
Publications - 24
Citations - 499
Fang Ji is an academic researcher from National University of Singapore. The author has contributed to research in topics: White matter & Medicine. The author has an hindex of 11, co-authored 20 publications receiving 330 citations. Previous affiliations of Fang Ji include University Health System & Nanjing Medical University.
Papers
More filters
Journal ArticleDOI
Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer's disease with and without cerebrovascular disease.
Fang Ji,Ofer Pasternak,Siwei Liu,Yng Miin Loke,Boon Linn Choo,Saima Hilal,Xin Xu,Mohammad Kamran Ikram,Narayanaswamy Venketasubramanian,Christopher Chen,Juan Zhou,Juan Zhou +11 more
TL;DR: The findings suggest that free water analysis isolates probable mild vascular damage from WM microstructural alterations and underscore the importance of normal-appearing WM changes underlying cognitive and functional impairment in AD with and without cerebrovascular disease.
Journal ArticleDOI
Disrupted salience network functional connectivity and white-matter microstructure in persons at risk for psychosis: findings from the LYRIKS study.
Chenhao Wang,Fang Ji,Z. Hong,Joann S. Poh,Ranga Krishnan,Jimmy Lee,Gurpreet Rekhi,Richard S.E. Keefe,R. A. Adcock,Stephen J. Wood,Alex Fornito,Ofer Pasternak,Michael W. L. Chee,Juan Zhou +13 more
TL;DR: The findings support the insular dysconnectivity of the proximal SN hypothesis in the early stages of psychosis and the combined structural and functional SN assays may inform the prognosis of persons at-risk for psychosis.
Journal ArticleDOI
STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs
Gisela Garcia-Alvarez,Bo Lu,Kenrick An Fu Yap,Loo Chin Wong,Jervis Vermal Thevathasan,Lynette Lim,Fang Ji,Kia Wee Tan,James J. Mancuso,Willcyn Tang,Shou Yu Poon,George J. Augustine,Marc Fivaz +12 more
TL;DR: STIMs (STIM1 and STIM2 in mammals) are transmembrane proteins that reside in the endoplasmic reticulum and regulate store-operated Ca2+ entry and mediates cAMP/PKA-dependent phosphorylation of the AMPA receptor subunit GluA1 in excitatory neurons.
Journal ArticleDOI
Role of glycine receptors in glycine-induced LTD in hippocampal CA1 pyramidal neurons.
Rongqing Chen,Shan-Hui Wang,Wen Yao,Jing-Jing Wang,Fang Ji,Jing-Zhi Yan,Si-Qiang Ren,Zheng Chen,Su-Yi Liu,Wei Lu +9 more
TL;DR: The present findings reveal an important function of GlyR activation and modulation in gating the direction of synaptic plasticity, and suggest that GlyRs are involved in Gly-LTD.
Journal ArticleDOI
Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer's Disease and Amnestic Mild Cognitive Impairment.
Yi Jayne Tan,Yi Jayne Tan,Adeline S.L. Ng,Ashwati Vipin,Joseph Lim,Russell J. Chander,Fang Ji,Yingwei Qiu,Simon Kang Seng Ting,Shahul Hameed,Tih-Shih Lee,Li Zeng,Nagaendran Kandiah,Juan Zhou,Juan Zhou +14 more
TL;DR: Peripheral TREM2 mRNA levels are higher in AD and are associated with AD-related cognitive deficits and hippocampal atrophy, suggesting that TREM 2 may be a potential non-invasive peripheral biomarker for AD diagnosis.