F
Faouzi Braza
Researcher at French Institute of Health and Medical Research
Publications - 31
Citations - 1609
Faouzi Braza is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Regulatory B cells & House dust mite. The author has an hindex of 18, co-authored 31 publications receiving 1260 citations. Previous affiliations of Faouzi Braza include Centre national de la recherche scientifique & University of Nantes.
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Journal ArticleDOI
IL-17 in severe asthma. Where do we stand?
TL;DR: The implications of IL-17 in the induction of neutrophilic airway inflammation, steroid insensitivity, the epithelial cell profile, and airway remodeling are discussed.
Journal ArticleDOI
Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties
Mélanie Chesneau,Laure Michel,Emilie Dugast,Alexis Chenouard,Alexis Chenouard,Daniel Baron,Daniel Baron,Annaïck Pallier,Justine Durand,Justine Durand,Faouzi Braza,Faouzi Braza,Pierrick Guerif,David-Axel Laplaud,David-Axel Laplaud,Jean-Paul Soulillou,Jean-Paul Soulillou,Magali Giral,Magali Giral,Nicolas Degauque,Nicolas Degauque,Elise Chiffoleau,Elise Chiffoleau,Sophie Brouard,Sophie Brouard +24 more
TL;DR: Insight is provided into the characterization of B cell-mediated immunoregulation in clinical tolerance and a potential regulatory effect of B cells on effector T cells in blood from patients with operationally tolerant kidney grafts are shown.
Journal ArticleDOI
Unique B cell differentiation profile in tolerant kidney transplant patients.
Mélanie Chesneau,A. Pallier,Faouzi Braza,Faouzi Braza,gersende lacombe,S. Le Gallou,Daniel Baron,Magali Giral,Magali Giral,Richard Danger,Richard Danger,Pierrick Guerif,H. Aubert-Wastiaux,Antoine Néel,Antoine Néel,Laure Michel,Laure Michel,David-Axel Laplaud,David-Axel Laplaud,Nicolas Degauque,Jean-Paul Soulillou,Jean-Paul Soulillou,Karin Tarte,Sophie Brouard,Sophie Brouard +24 more
TL;DR: The data suggest that a balance between B cells producing IL‐10 and a deficiency in plasma cells may encourage an environment favorable to the tolerance maintenance, and down‐regulation of B cell differentiation genes and anti‐apoptotic B cell genes in these patients in vivo.
Journal ArticleDOI
Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma.
Faouzi Braza,Faouzi Braza,S. Dirou,Virginie Forest,Virginie Forest,Vincent Sauzeau,Vincent Sauzeau,Dorian Hassoun,Dorian Hassoun,Julie Chesné,Julie Chesné,Marie-Aude Cheminant-Muller,Marie-Aude Cheminant-Muller,Christine Sagan,Antoine Magnan,Patricia Lemarchand +15 more
TL;DR: The results of this study indicate that MSCs attenuate asthma by being phagocyted by lung macrophages, which in turn acquire a M2 suppressive phenotype.
Journal ArticleDOI
Role of TLRs and DAMPs in allograft inflammation and transplant outcomes
TL;DR: Exogenous substances — damage-associated molecular patterns (DAMPs) — that are released after allograft reperfusion and induce inflammation and innate immune signalling pathways that are activated after solid organ transplantation are described, with a focus on Toll-like receptors and their signal adaptor, MYD88.