A
Antoine Magnan
Researcher at University of Nantes
Publications - 259
Citations - 8893
Antoine Magnan is an academic researcher from University of Nantes. The author has contributed to research in topics: Asthma & Allergy. The author has an hindex of 47, co-authored 242 publications receiving 7570 citations. Previous affiliations of Antoine Magnan include Ludwig Maximilian University of Munich & Centre national de la recherche scientifique.
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Journal ArticleDOI
Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
TL;DR: It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.
Journal ArticleDOI
Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial.
Geoffrey Chupp,Eric S. Bradford,Frank C. Albers,Daniel J. Bratton,Jie Wang-Jairaj,Linda M. Nelsen,Jennifer Trevor,Antoine Magnan,Anneke ten Brinke +8 more
TL;DR: Mepolizumab was associated with significant improvements in HRQOL in patients with severe eosinophilic asthma, and had a safety profile similar to that of placebo, and these results add to and support the use of mepolizumAB as a favourable add-on treatment option to standard of care.
Journal ArticleDOI
IL-17 in severe asthma. Where do we stand?
TL;DR: The implications of IL-17 in the induction of neutrophilic airway inflammation, steroid insensitivity, the epithelial cell profile, and airway remodeling are discussed.
Journal Article
Platelet-derived growth factor expression in primary pulmonary hypertension: comparison of HIV seropositive and HIV seronegative patients.
Marc Humbert,Gianpaola Monti,Muriel Fartoukh,Antoine Magnan,F Brenot,Bernadette Rain,Frédérique Capron,Pierre Galanaud,Pierre Duroux,G. Simonneau,Dominique Emilie +10 more
TL;DR: A possible role for PDGF in PPH occurring in HIV seropositive and seronegative patients is documented and growth factors such as platelet-derived growth factor may play a part in the initiation and/or progression of primary pulmonary hypertension.
Journal ArticleDOI
Importance of inhaler devices in the management of airway disease
Johann Christian Virchow,Graham K. Crompton,R. W. Dal Negro,Shona Pedersen,Antoine Magnan,J. Seidenberg,Peter J. Barnes +6 more
TL;DR: Improvements in using inhalation devices more efficiently, in inhaler design for supporting patient compliance, and advances in inhalers technology to assure drug delivery to the lungs, have the potential to improve asthma and COPD management and control.