Farzin Haque

TL;DR: The three-way junction domain of the phi29 bacteriophage can be assembled from three pieces of RNA oligomers to form stable multifunctional nanoparticles that are useful for the treatment of different diseases.

TL;DR: This review covers current nanopore detection platforms including both biological pores and solid state counterparts and focuses on the three best characterized systems including α-hemolysin and MspA, both containing a smaller channel for the detection of single-strand DNA, as well as bacteriophage phi29 DNA packaging motor connector that contains a larger channel forThe passing of double stranded DNA.

TL;DR: The orientation of arrow-shaped RNA was altered to control ligand display on extracellular vesicle membranes for specific cell targeting, or to regulate intracellular trafficking of small interfering RNA (siRNA) or microRNA (miRNA) in cancer treatment.

TL;DR: This review aims to outline the current state of the art of RNA nanoparticles as programmable smart complexes and offers perspectives on the promising avenues of research in this fast-growing field.

TL;DR: The application of RNA nanotechnology for specific and efficient delivery of anti-miR-21 to block the growth of TNBC in orthotopic mouse models is reported here and demonstrates the clinical potentials ofRNA nanotechnology based platform to deliver miRNA based therapeutics for cancer treatment.