Federica Zamporlini

TL;DR: It is demonstrated that edible insects powder can successfully be included in leavened baked goods to enhance their protein content, proving that edible Insects can constitute a novel source of innovative ingredients to be used in bread making.

TL;DR: Results of sensory analyses revealed that protein fortification of bread with MP significantly affected bread texture and overall liking, as well as crust colour, depending on the substitution level, suggesting that the production of breads with MP might easily be scaled up at industrial level.

TL;DR: NMN deamidase reduces NMN accumulation in injured mouse sciatic nerves and preserves some axons for up to three weeks, even when expressed at a low level, and rescues axonal outgrowth and perinatal lethality in a dose-dependent manner in mice lacking NMNAT2.

TL;DR: The results indicate that the pharmacological inhibition of CD73 enzymatic activity could be considered as a means to potentiate the anti-cancer effects of NAMPT inhibitors.

TL;DR: The identification of Vacor as a substrate metabolized by the consecutive action of NAMPT and NMNAT2 into the NAD analog Vacor adenine dinucleotide (VAD) causes unprecedented rapid NAD depletion, glycolytic block, energy failure, and necrotic death of NM NAT2-proficient cancer cells.