Feiko O. ter Kuile

TL;DR: It is suggested that preventative strategies implementable before or early in pregnancy, such as insecticide-treated net usage in women of child-bearing age or any future vaccine, could substantially reduce the number of women who experience placental infection.

TL;DR: There is an urgent need to develop targeted pharmacovigilance systems to assess the safety of antimalarials in early pregnancy, according to Feiko ter Kuile and colleagues.

TL;DR: Treatment guidelines should ensure that adequate doses are given from the initial deployment of antimalarials onward, as results raise concern about the longevity of sulfadoxine-pyrimethamine in these settings.

TL;DR: Both seasonal effects and number of children per household had larger impacts than ITNs on health care expenditures and time lost from household activities, and the widespread adoption of the ITNs will therefore probably require a subsidy.

TL;DR: Genotyping of P. vivax showed that activation of related (homologous) hypnozoites was the most frequent cause of recurrence, and the high proportion of the impaired CYP2D6 activity among patients with recurrent infections suggests that slow primaquine metabolism might influence related relapse rates in Brazil among patients receivingPrimaquine for radical cure, although confirmatory studies are needed.