Felix Müller

TL;DR: In addition to marked hallucinogenic effects, LSD exerts methylenedioxymethamphetamine-like empathogenic mood effects that may be useful in psychotherapy, supporting the use of LSD in translational psychiatric research.

TL;DR: The effects of LSD on emotion processing and sociality may be useful for LSD-assisted psychotherapy.

TL;DR: Investigation of the acute autonomic, subjective, and endocrine effects of single doses of LSD, MDMA, and d-amphetamine in 28 healthy subjects indicates clearly distinct acute effects and may assist the dose-finding in substance-assisted psychotherapy research.

TL;DR: It is demonstrated that psilocybin induced region-dependent alterations in glutamate, which predicted distortions in the subjective experience of one’s self (ego dissolution), which may provide a neurochemical basis for therapeutic effects as witnessed in ongoing clinical trials.

TL;DR: In a double-blind, randomized, cross-over study, 100 μg LSD and placebo were orally administered to 20 healthy participants and seed-to-voxel analyses consistently indicated increased connectivity between networks and subcortical and cortical hub structures, consistent with findings on the importance of hubs in psychopathological states, especially in psychosis.