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Felix Zeppernick
Researcher at Heidelberg University
Publications - 15
Citations - 919
Felix Zeppernick is an academic researcher from Heidelberg University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 854 citations.
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Journal ArticleDOI
Stem cell marker CD133 affects clinical outcome in glioma patients.
Felix Zeppernick,Rezvan Ahmadi,Benito Campos,Christine Dictus,Burkhard Helmke,Natalia Becker,Peter Lichter,Andreas W. Unterberg,Bernhard Radlwimmer,Christel Herold-Mende +9 more
TL;DR: These findings constitute the first conclusive evidence that CD133 stem cell antigen expression correlates with patient survival in gliomas, lending support to the current cancer stem cell hypothesis.
Journal ArticleDOI
Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
Benito Campos,Feng Wan,Feng Wan,Mohammad Farhadi,Aurélie Ernst,Felix Zeppernick,Katrin E. Tagscherer,Rezvan Ahmadi,Jennifer Lohr,Christine Dictus,Georg Gdynia,Stephanie E. Combs,Violaine Goidts,Burkhard Helmke,Volker Eckstein,Wilfried Roth,Philipp Beckhove,Peter Lichter,Andreas Unterberg,Bernhard Radlwimmer,Christel Herold-Mende +20 more
TL;DR: It is shown that all-trans retinoic acid treatment alone can induce antitumor effects in vivo, and the potential of differentiation treatment to target the stem-like cell population in glioblastoma is highlighted.
Journal ArticleDOI
Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
Martin Reichert,Massimo Sartelli,Markus A. Weigand,Matthias Hecker,P. Oppelt,Julia Noll,I. Askevold,Juliane Liese,Winfried Padberg,Federico Coccolini,Fausto Catena,Andreas Hecker,Adam Peckham-Cooper,Adrián Camacho-Ortiz,Aikaterini Mastoraki,Aitor Landaluce-Olavarria,Ajay Kumar Pal,Akira Kuriyama,Alain Chichom-Mefire,Alberto Porcu,Aleix Martínez-Pérez,Aleksandar Karamarkovic,A.V. Osipov,Alessandro Coppola,Alessandro Cucchetti,A. Spolini,A. Giordano,Alexander Reinisch-Liese,Alfie Jose Kavalakat,Alin Vasilescu,Amin Ata Alamin,Amit Gupta,Ana Maria Dascalu,Ana Maria Mușină,Anargyros Bakopoulos,Andee Dzulkarnaen Zakaria,András Vereczkei,Andrea Balla,Andrea Bottari,Andreas Baumann,Andreas Fette,Andrey Litvin,Aniella Katharina Reichert,Anna Guariniello,Anna Paspala,Anne-Sophie Schneck,Antonio Brillantino,Antonio Pesce,Arda Isik,Ari Leppäniemi,A. Papadopoulos,Aristotelis Kechagias,Ashraf Yehya Abdalla Mohamed,Ashrarur Rahman Mitul,Athanasios Marinis,Athanasios Syllaios,Baris Mantoglu,Belinda De Simone,Benjamin Stefan Weiss,Bernd Pösentrup,Biagio Picardi,Biagio Zampogna,Boris Sakakushev,B. Atanasov,Bruno Nardo,Bulent Calik,Camilla Cremonini,Carlos A. Ordoñez,Charalampos Seretis,Chiara Cascone,C. Chouliaras,Cino Bendinelli,C. Lopes,Claudio Guerci,Clemens Weber,Constantinos Nastos,Cristian Mesina,Damiano Caputo,Damien Massalou,V. Cavaliere,Deborah A. McNamara,Demetrios Demetriades,D Pantalone,D. Coletta,Diego Sasia,D Visconti,Dieter G. Weber,Diletta Corallino,Dimitrios Chatzipetris,Dimitrios K. Manatakis,Dimitrios Ntourakis,Dimitrios Papaconstantinou,Dimitrios Schizas,Dimosthenis Chrysikos,Dmitry Mikhailovich Adamovich,D. S. Elkafrawy,Dragos Seban,Edgar Garcia,Edoardo Baldini,Edoardo Picetti,Edward Tan,Efstratia Baili,Eftychios Lostoridis,Elena-Adelina Toma,Elif Colak,Elisabetta Cerutti,Elmin Steyn,Elmuiz A. Hsabo,Emmanouil I. Kapetanakis,Emmanouil Kaouras,Emmanuel Schneck,Emrah Akin,Emre Gonullu,Enes Celik,Enrico Cicuttin,Enrico Pinotti,Erik L. Johnsson,Ernest E. Moore,E Agastra,Evgeni N Dimitrov,J. Griffiths,Fabrizio D'Acapito,Federica Saraceno,Felipe Alconchel,Felix Zeppernick,Fernando Rodríguez,Fikri M. Abu-Zidan,Francesca Pecchini,Francesco Favi,F. Ferrara,Francesco Fleres,Francesco Pata,Francesco Roscio,Frank J. M. F. Dor,Fredrik Linder,G Dimofte,Gabriel Rodrigues,Gabriela Elisa Nita,Gabriele Sganga,G. Martines,Gennaro Mazzarella,Gennaro Perrone,George C. Velmahos,Georgios D Lianos,G. Tomadze,Gian Luca Baiocchi,Giancarlo D'Ambrosio,Gianluca Pellino,Gian Maria Casoni Pattacini,Giorgio Giraudo,Giorgio Lisi,Giovanni D. Tebala,Giovanni Pirozzolo,Giulia Montori,G. F. Argenio,Giuseppe Brisinda,Giuseppe Currò,Giuseppe Giuliani,G. Palomba,Giuseppe Roscitano,Gökhan Avşar,M. Augustin,Guglielmo Clarizia,Gustavo M. Machain Vega,Gustavo Pereira Fraga,Harsh Sethi,Hazim Eltyeb,Helmut Alfredo Segovia Lohse,H. A. Segovia Lohse,Huseyin Bayhan,Hytham K.S. Hamid,I.A. Kryvoruchko,I Iannone,Imtiaz Wani,Ioannis Lazaridis,Ioannis Katsaros,Ioannis Nikolopoulos,Ionut Negoi,Isabella Reccia,Isidoro Di Carlo,Iyiade Olaoye,Jacek Czepiel,Jae Il Kim,Jeremy Meyer,Jesús Manuel Saénz-Terrazas,Joel Noutakdie Tochie,Joseph M. Galante,Justin Davies,Kapil Sugand,K. B. Gonfa,Kemal Rasa,Kenneth Y.Y. Kok,Konstantinos Apostolou,Konstantinos Lasithiotakis,Konstantinos Tsekouras,Kumar Angamuthu,Lali Akhmeteli,Larysa Sydorchuk,Laura Fortuna,Leandro Siragusa,Leonardo Pagani,Leonardo Solaini,Lisa A. Miller,Lovenish Bains,Luca Ansaloni,Luca Ferrario,Luigi Bonavina,Luigi Conti,L. Buonomo,Luis Tallón-Aguilar,Lukasz Tomczyk,Lukas W. Widmer,Maciej Walędziak,Mahir Gachabayov,Maloni Bulanauca,Manu L N G Malbrain,M. Maegele,Marco Catarci,Marco Ceresoli,Maria Chiara Ranucci,Maria Antonopoulou,Maria Papadoliopoulou,Maria Rosaria Valenti,Maria Sotiropoulou,Mario D'Oria,Mario Serradilla-Martin,Markus Hirschburger,Massimiliano Veroux,Massimo Fantoni,Matteo Nardi,Matti Tolonen,Mauro Montuori,Mauro Podda,M. Scheiterle,Maximos Frountzas,Mehmet Ali Sarikaya,Mehmet Yildirim,Michael Mclean Bender,Michail Vailas,Michel Teuben,Michela Campanelli,Michele Ammendola,Michele Malerba,Michele Pisano,Mihaela Pertea,M. Slavchev,Mika Ukkonen,Miklosh Bala,Mircea Chirica,Mirko Barone,M. Shaat,Mohammed Jibreel Suliman Mohammed,M Abuelgasim,Monika Gureh,Mouaqit Ouadii,Müjdat Balkan,Mumin Maslah Mohamed,Musluh Hakseven,Natalia Velenciuc,Nicola Cillara,Nicola de’Angelis,Nicolò Tamini,Nikolaos Zavras,Nikolaos Machairas,Nikolaos V. Michalopoulos,Nikolaos Koliakos,Nikolaos Pararas,Noel E Donlon,Noushif Medappil,Offir Ben-Ishay,Olmi Stefano,Omar Islam,Ömer Tammo,Orestis Ioannidis,Oscar Aparicio,Oussama Baraket,Pankaj Kumar,Pasquale Cianci,Per Örtenwall,Petar A Uchikov,Philip R. de Reuver,Philip D. Stahl,Philip S. Barie,Micaela Piccoli,Piotr Major,Pradeep H. Navsaria,Prakash Kumar Sasmal,R. Coimbra,Razrim Rahim,Recayi Capoglu,Renol M. Koshy,Ricardo Alessandro Teixeira Gonsaga,Riccardo Pertile,Rif Mohamed,Rıza Deryol,Robert G. Sawyer,Roberta Angelico,Roberta Ragozzino,R M Bini,Robert C. Cammarata,Rosa T. Scaramuzzo,Rossella Gioco,R. Sydorchuk,Salma Hayder Ahmed,S. Di Saverio,Sameh Hany Emile,Samir Delibegovic,Sanjay Marwah,Savvas Symeonidis,Scott G. Thomas,Sebahattin Demir,Selmy Awad,Semra Demirli Atici,Serge Chooklin,Serhat Meriç,Sevcan Sarikaya,Sharfuddin Chowdhury,Shaza Faycal Mirghani,Sherry M. Wren,Simone Gargarella,Simone Rossi Del Monte,S. Esposito,Sofia Xenaki,Soliman Mohamed,Solomon Beka,Sorinel Lunca,Spiros Delis,S. Dritsas,Stefan Morarasu,Stefano Magnone,Stefano Rossi,Stefanos Bitsianis,Stylianos Kykalos,Suman Baral,Sumita Jain,Syed Muhammad Ali,Tadeja Pintar,Tania Triantafyllou,Tarik Delko,T. Perra,Theodoros Sidiropoulos,Thomas M. Scalea,Tim O. Vilz,Timothy Craig Hardcastle,Tongporn Wannatoop,Torsten Herzog,Tushar Subhadarshan Mishra,Ugo Boggi,V. Calu,Valentina Tomajer,Vanni Agnoletti,Varut Lohsiriwat,Victor Kong,Virginia Durán Muñoz-Cruzado,Vishal G Shelat,Vladimir Khokha,Wagih Ghannam,Walter L. Biffl,Wietse P. Zuidema,Yasin Kara,Yoshiro Kobe,Zaza Demetrashvili,Ziad A. Memish,Zoilo Madrazo,Zsolt J. Balogh,Zülfü Bayhan +365 more
TL;DR: The second WSES COVID-19 emergency surgery survey investigates the impact of the SARS-CoV-2 pandemic on emergency surgery during the course of the pandemic as discussed by the authors .
Journal ArticleDOI
EpCAM- and EGFR-Specific Antibody Drug Conjugates for Triple-Negative Breast Cancer Treatment
Chaoyu Zhang,W. Sheng,Marwah Firas Al-Rawe,TM Mohiuddin,Marcus Niebert,Felix Zeppernick,Ivo Meihold-Heerlein,Ahmad Fawzi Hussain +7 more
TL;DR: This study demonstrated that EGFR specific scFv-425-SNAP-BG-MMAE and EpCAM-specific scFV-EpCAM - SNAP- BG-M MAE could be promising ADCs for the treatment of TNBC.
Journal ArticleDOI
Multiplex Immunofluorescence: A Powerful Tool in Cancer Immunotherapy
W. Sheng,Chao Zhang,TM Mohiuddin,Marwah Firas Al-Rawe,Felix Zeppernick,Franco H. Falcone,Ivo Meinhold-Heerlein,Ahmad Fawzi Hussain +7 more
TL;DR: In this article , a review summarizes the technologies which are applied for multiplex immunohistochemistry (mIHC) and discusses how they are employed for immunotherapy research for cancer immunotherapy.