F
Feng-Mao Lin
Researcher at National Chiao Tung University
Publications - 17
Citations - 3108
Feng-Mao Lin is an academic researcher from National Chiao Tung University. The author has contributed to research in topics: MiRTarBase & Human genome. The author has an hindex of 10, co-authored 17 publications receiving 2518 citations. Previous affiliations of Feng-Mao Lin include City of Hope National Medical Center & National Central University.
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Journal ArticleDOI
miRTarBase: a database curates experimentally validated microRNA–target interactions
Sheng Da Hsu,Feng-Mao Lin,Wei-Yun Wu,Chao Liang,Wei Chih Huang,Wen-Ling Chan,Wen-Ting Tsai,Goun-Zhou Chen,Chia-Jung Lee,Chih Min Chiu,Chia-Hung Chien,Ming-Chia Wu,Chi Ying F. Huang,Ann-Ping Tsou,Hsien Da Huang +14 more
TL;DR: The miRTarBase contains the largest amount of validated MTIs by comparing with other similar, previously developed databases and can also provide a large amount of positive samples to develop computational methods capable of identifying miRNA–target interactions.
Journal ArticleDOI
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions
Sheng Da Hsu,Yu-Ting Tseng,Sirjana Shrestha,Yu Ling Lin,Anas Khaleel,Chih Hung Chou,Chao-Fang Chu,Hsi-Yuan Huang,Ching-Min Lin,Shu Yi Ho,Jian Ting-Yan,Feng-Mao Lin,Tzu Hao Chang,Shun-Long Weng,Shun-Long Weng,Shun-Long Weng,Kuang-Wen Liao,I-En Liao,Chun-Chi Liu,Hsien Da Huang +19 more
TL;DR: The miRTarBase database (http://mirtarbase.mbc.nctu.edu.tw/) provides the most current and comprehensive information of experimentally validated miRNA-target interactions, with a 14-fold increase to mi RNA-target interaction entries and recent improvements.
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Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes.
Qiang Cai,Lulu Qiao,Lulu Qiao,Ming Wang,Baoye He,Feng-Mao Lin,Jared Palmquist,Sienna-Da Huang,Hailing Jin +8 more
TL;DR: It is shown that host Arabidopsis cells secrete exosome-like extracellular vesicles to deliver sRNAs into fungal pathogen Botrytis cinerea, which induce silencing of fungal genes critical for pathogenicity.
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Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis
Zhen Chen,Tsung-Ching Lai,Yi-Hua Jan,Feng-Mao Lin,Wei-Chi Wang,Han Xiao,Yun-Ting Wang,Wei Sun,Xiaopei Cui,Ying-Shiuan Li,Tzan Fang,Hongwei Zhao,Chellappan Padmanabhan,Ruobai Sun,Danny Ling Wang,Hailing Jin,Gar-Yang Chau,Hsien Da Huang,Michael Hsiao,John Y.-J. Shyy +19 more
TL;DR: Data from tumor xenografts and human cancer specimens indicate that AGO1-mediated translational desuppression of VEGF may be associated with tumor angiogenesis and poor prognosis and suggest that this pathway may be a suitable target for anti- or proangiogenesis strategies.
Journal ArticleDOI
Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
Yu-Ching Teng,Cheng-Feng Lee,Ying-Shiuan Li,Yi-Ren Chen,Pei-Wen Hsiao,Meng-Yu Chan,Feng-Mao Lin,Hsien Da Huang,Yen-Ting Chen,Yung-Ming Jeng,Chih-Hung Hsu,Qin Yan,Ming-Daw Tsai,Li-Jung Juan +13 more
TL;DR: An oncogenic role forRBP2 in lung tumorigenesis and progression is established and novel RBP2 targets mediating this role are uncovered and uncovered.