F
Fiona E. McAllister
Researcher at Harvard University
Publications - 38
Citations - 2420
Fiona E. McAllister is an academic researcher from Harvard University. The author has contributed to research in topics: Proteome & Proteomics. The author has an hindex of 19, co-authored 33 publications receiving 1954 citations. Previous affiliations of Fiona E. McAllister include Australian Institute of Marine Science & University of Edinburgh.
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Journal ArticleDOI
Practitioner Review: Engaging fathers – recommendations for a game change in parenting interventions based on a systematic review of the global evidence
Catherine Panter-Brick,Adrienne Burgess,Mark Eggerman,Fiona E. McAllister,Kyle D. Pruett,James F. Leckman +5 more
TL;DR: Barriers to engaging men as parents work against father inclusion as well as father retention, and undervalue coparenting as contrasted with mothering, which will constitute a game change in this field.
Journal ArticleDOI
iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis
David C. Schöndorf,Massimo Aureli,Fiona E. McAllister,Christopher J. Hindley,Florian Mayer,Benjamin Schmid,S. Pablo Sardi,Manuela Valsecchi,Susanna A. Hoffmann,Lukas Kristoffer Schwarz,Ulrike Hedrich,Daniela Berg,Lamya S. Shihabuddin,Jing Hu,Jan Pruszak,Steven P. Gygi,Sandro Sonnino,Thomas Gasser,Michela Deleidi +18 more
TL;DR: Induced pluripotent stem cells are generated from subjects with GD and PD harbouring GBA1 mutations and complex changes in the autophagic/lysosomal system and intracellular calcium homeostasis, which underlie vulnerability to neurodegeneration are provided.
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An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ
Alexander S. Banks,Fiona E. McAllister,Joao Paulo Camporez,Peter-James H. Zushin,Michael J. Jurczak,Dina Laznik-Bogoslavski,Gerald I. Shulman,Steven P. Gygi,Bruce M. Spiegelman +8 more
TL;DR: Pharmacological inhibition of MEK and ERK markedly improves insulin resistance in both obese wild-type and ob/ob mice, and also completely reverses the deleterious effects of the Cdk5 ablation, suggesting that MEK/ERK inhibitors may hold promise for the treatment of type 2 diabetes.
Journal ArticleDOI
Chaperone-mediated pathway of proteasome regulatory particle assembly
Jeroen Roelofs,Soyeon Park,Wilhelm Haas,Geng Tian,Fiona E. McAllister,Ying Huo,Byung-Hoon Lee,Fan Zhang,Yigong Shi,Steven P. Gygi,Daniel Finley +10 more
TL;DR: It is shown that in the yeast Saccharomyces cerevisiae three proteins are found associated with RP but not with the RP–CP holoenzyme: Nas6, Rpn14 and Hsm3 are RP chaperones, and it is shown in an accompanying study that RP assembly is templated through the Rpt C termini, apparently by their insertion into binding pockets in the CP.
Journal ArticleDOI
Prokayrotic Ubiquitin-Like Protein (Pup) Proteome of Mycobacterium tuberculosis
Richard A. Festa,Fiona E. McAllister,Michael J. Pearce,Julian Mintseris,Kristin E. Burns,Steven P. Gygi,K. Heran Darwin +6 more
TL;DR: Data demonstrate that pupylation regulates numerous proteins in Mtb and may not always lead to degradation, as well as identifying its "pupylome" using tandem affinity purification.