Florence Bansept

TL;DR: It is shown that a different physical process drives formation of clumps in vivo: IgA-mediated cross-linking enchains daughter cells, preventing their separation after division, and clumping is therefore dependent on growth.

TL;DR: In this paper, the authors evaluate the key stages of the biphasic life cycle and propose a new conceptual framework for microbiota-host interactions which includes an integrative measure of microbial fitness, related to the parasite fitness parameter R0, and which will help in-depth assessment of these widespread associations.

TL;DR: The authors' models show robustly that at higher replication rates, bacteria replicate before the link between daughter bacteria breaks, leading to growing cluster sizes, while at low growth rates two daughter bacteria have a high probability to break apart, and the gut could produce IgA against all the bacteria it has encountered, but the most affected bacteria would be the fast replicating ones that are more likely to destabilize the microbiota.

TL;DR: In this article, the authors investigate a simple model of a microbial lineage living, replicating, migrating and competing in and between two compartments: a host and an environment, and focus on the direction of selection at each point of the phenotypic space, defining an optimal way for the microbial lineage to increase its fitness.

TL;DR: Using analytical and numerical calculations on several models to check the results robustness, the rate of increase in the number of free bacteria as a function of the replication rate of bacteria, and the resulting distribution of chain sizes is studied.