F
Florian Hohla
Researcher at Paracelsus Private Medical University of Salzburg
Publications - 37
Citations - 1957
Florian Hohla is an academic researcher from Paracelsus Private Medical University of Salzburg. The author has contributed to research in topics: Receptor & In vivo. The author has an hindex of 22, co-authored 37 publications receiving 1645 citations. Previous affiliations of Florian Hohla include University of Salzburg & Veterans Health Administration.
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Journal ArticleDOI
FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis
Mustafa Suker,Berend R. Beumer,Eran Sadot,Lysiane Marthey,Jason E. Faris,Eric A. Mellon,Bassel F. El-Rayes,Andrea Wang-Gillam,Jill Lacy,Peter J. Hosein,Sing Yu Moorcraft,Thierry Conroy,Florian Hohla,Peter J. Allen,Julien Taieb,Theodore S. Hong,Ravi Shridhar,Ian Chau,Casper H.J. van Eijck,Bas Groot Koerkamp +19 more
TL;DR: Patients with locally advanced pancreatic cancer treated with FOLFIRINOX had a median overall survival of 24·2 months-longer than that reported with gemcitabine (6-13 months).
Journal ArticleDOI
A role for low hepatic copper concentrations in nonalcoholic Fatty liver disease.
Elmar Aigner,Michael Strasser,Heike Haufe,Thomas Sonnweber,Florian Hohla,Andreas Stadlmayr,Marc Solioz,Herbert Tilg,Wolfgang Patsch,Guenter Weiss,Felix Stickel,Christian Datz +11 more
TL;DR: Reduced hepatic copper concentrations are found in human NAFLD and are associated with more pronounced hepatic steatosis, NASH, and components of the metabolic syndrome.
Journal ArticleDOI
Copper availability contributes to iron perturbations in human nonalcoholic fatty liver disease.
Elmar Aigner,Igor Theurl,Heike Haufe,Markus Seifert,Florian Hohla,Ludwig Scharinger,Felix Stickel,Frédéric Mourlane,Günter Weiss,Christian Datz +9 more
TL;DR: The results indicate that copper status is linked to iron homeostasis in NAFLD, suggesting that low copper bioavailability causes increased hepatic iron stores via decreased FP-1 expression and ceruloplasmin ferroxidase activity thus blocking liver iron export in copper-deficient subjects.
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Nonalcoholic fatty liver disease: an independent risk factor for colorectal neoplasia.
Andreas Stadlmayr,Elmar Aigner,B. Steger,L. Scharinger,Dieter Lederer,Astrid Mayr,Michael Strasser,Eric J. Brunner,A. Heuberger,Florian Hohla,J. Steinwendner,Wolfgang Patsch,Christian Datz +12 more
TL;DR: Nonalcoholic fatty liver disease is an independent risk factor for colorectal neoplasia and should be considered as a standalone risk factor, rather than a double-edged sword for cancer diagnosis.
Journal ArticleDOI
Antagonists of growth hormone-releasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinases
Ferenc G. Rick,Andrew V. Schally,Luca Szalontay,Norman L. Block,Karoly Szepeshazi,Mehrdad Nadji,Marta Zarandi,Marta Zarandi,Florian Hohla,Florian Hohla,Stefan Buchholz,Stefan Buchholz,Stefan Buchholz,Stephan Seitz,Stephan Seitz +14 more
TL;DR: The findings support the role of G HRH as an autocrine growth factor in prostate cancer and suggest that antagonists of GHRH should be considered for further development as therapy for CRPC.