F
Francesca Levi-Schaffer
Researcher at Hebrew University of Jerusalem
Publications - 337
Citations - 17612
Francesca Levi-Schaffer is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Mast cell & Eosinophil. The author has an hindex of 65, co-authored 318 publications receiving 16028 citations. Previous affiliations of Francesca Levi-Schaffer include National Institutes of Health & Weizmann Institute of Science.
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Journal ArticleDOI
Role of reactive oxygen species (ROS) in apoptosis induction
TL;DR: The role of ROS in the regulation of apoptosis, especially in inflammatory cells, is focused on, with particular attention to mitochondria.
Journal ArticleDOI
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
Simon D. Harding,Joanna L. Sharman,Elena Faccenda,Christopher Southan,Adam J. Pawson,Sam M. Ireland,Alasdair J. G. Gray,Liam Bruce,Stephen P.H. Alexander,Stephen M. Anderton,Clare E. Bryant,Anthony P. Davenport,Christian Doerig,Doriano Fabbro,Francesca Levi-Schaffer,Michael Spedding,Jamie A. Davies,Nc-Iuphar +17 more
TL;DR: This update describes content expansion, new features and interoperability improvements introduced in the 10 releases since August 2015, and introduces the newly funded project for the Guide to IMMUNOPHARMACOLOGY (GtoImmuPdb, www.guidetoimmunopharmacology.org).
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Coculture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells.
TL;DR: Mouse bone marrow-derived mast cells (BMMC), the probable in vitro counterparts of in vivo mucosal mast cells, were cultured for 14 days with mouse skin-derived 3T3 fibroblasts in RPMI 1640 medium containing 10% fetal calf serum and 50% WEHI-3 conditioned medium to induce a phenotypic change so that the resulting mast cells stain safranin+ and synthesize heparin proteoglycans.
Journal ArticleDOI
Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair.
Alessandra Micera,Eliana Vigneti,Dalia Pickholtz,Reuven Reich,Orit Pappo,Sergio Bonini,François-Xavier Maquart,Luigi Aloe,Francesca Levi-Schaffer +8 more
TL;DR: Data show a direct pro-fibrogenic effect of NGF on skin and lung fibroblasts and therefore indicate a role for NGF in tissue repair and fibrosis.