Showing papers by "Francesco Salvatore published in 2006"
01 Jan 2006
TL;DR: In this article, the authors present a joint experimental and theoretical research on an innovative technology for marine current exploitation based on the Kobold turbine concept, which has been realized and it is currently successfully operating in the Messina Strait in Italy since 2001.
Abstract: In this paper we present a joint experimental and theoretical research on an innovative technology for marine current exploitation based on the Kobold turbine concept. A prototype of this vertical-axis turbine has been realized and it is currently successfully operating in the Messina Strait in Italy since 2001. Different scale model configurations of Kobold turbine has been tested at the INSEAN towing tank at different sea current conditions. Those data will be used as benchmark for comparison with the numerical model predictions and as a source of information for the design of improved and optimized real prototypes. From a theoretical and computational perspective, a fully threedimensional unsteady hydrodynamic model has been developed based on a Boundary Element Method.
27 citations
TL;DR: The whole coding region and the 5′UTR of the MBL2 gene in DNA extracted from neoplastic cells embedded in paraffin sections from 145 unrelated patients affected by noncardia gastric cancer found to be related to Helicobacter pylori infection.
Abstract: El-Omar et al. (1) reported that interleukin (IL)-1 gene cluster variants that enhance the production of IL-1β (a powerful inhibitor of gastric acid secretion) increase the risk of gastric cancer in Helicobacter pylori (HP)-infected patients. IL-1β production is down-regulated by mannose-binding lectin (MBL) (2), an acute-phase glycoprotein that has a high affinity for gram-negative lipopolysaccharide and exerts immunological activity (3)(4). Variants in the promoter, the 5′UTR, and exon 1 of the MBL2 gene reduce the synthesis and activity of MBL (5).
To assess the relationships between MBL2 gene variants and HP-related gastric cancer, we analyzed the whole coding region and the 5′UTR of the MBL2 gene in DNA extracted (QIAamp, Qiagen) from neoplastic cells embedded in paraffin sections (used for histological diagnosis) from 145 unrelated patients (90 males) affected by noncardia gastric cancer. Eighty-seven (60.0%) had intestinal-type; 47 (32.4%), diffuse-type; and 11 (7.6%), mixed-type adenocarcinoma. All patients had HP-positive serology. For 75 patients, we …
26 citations
TL;DR: The possibility of an association between these 2 gastrointestinal disorders is important, particularly in the management of HFI patients with persisting symptoms, particularly for children in whom the CD-associated signs were hypertransaminasemia, failure to thrive, low weight, and short stature.
17 citations
TL;DR: Annexin VII was present in reticulocytes but was then lost as the cells matured, but a different pattern was found in band 3‐deficient samples: annexin VIII was in fact present in both mature and immature red cell membranes.
16 citations
TL;DR: A partial purification of the UN1 protein from HPB-ALL T cells by anion-exchange chromatography followed by immunoprecipitation with the UN 1 mAb and MALDI-TOF MS analysis should assist in identifying the amino acid sequence of UN1.
8 citations
TL;DR: The discordance of clinical expression within the same family reinforces the putative role of modifier genes of CF phenotype and reveals the rare F508del/D614G genotype.
7 citations
TL;DR: It is suggested that the phosphate binding and hydrolytic properties of mixtures containing Zn(II) ions and I should depend not only on the pH but also on the Zn:I ratio used.
Abstract: The dinucleating ligand 1,3-bis[bis(pyridin-2-ylmethyl)amino] propan-2-ol (I, LOH) is becoming of increasing interest due to the exceptional phosphate monoester binding and phosphate diester hydrolytic properties of its dizinc(II) complexes in water. Potentiometric pH titrations using a range of Zn:I ratios reveals the formation of mononuclear and dinuclear metal complexes. In fact, when the Zn:I ratio is 1:1 only mononuclear complexes are formed. Previous work reported the formation of only dinuclear species. Thus, the results presented here should be important to interpret correctly and more accurately phosphate ester binding and hydrolysis data. Moreover, based on these findings we suggest that the phosphate binding and hydrolytic properties of mixtures containing Zn(II) ions and I should depend not only on the pH but also on the Zn:I ratio used.
5 citations
TL;DR: CMRL-T as discussed by the authors is a novel T-cell line showing asynchronous phenotype (CD34+/CD1a−/TCR αβ +) and dual Tcell receptor β chain.
Abstract: CMRL-T, a novel T-cell line showing asynchronous phenotype (CD34+/CD1a−/TCR αβ +) and dual T-cell receptor β chain
2 citations