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Showing papers in "International Journal of Biological Macromolecules in 2006"


Journal ArticleDOI
TL;DR: It has been found that the TUCS is a much better fungicidal agent (about 60 times more) than the pure CS against most of the fungal strains tested.

216 citations


Journal ArticleDOI
TL;DR: The rheological behavior of aqueous solutions of gum tragacanth and its insoluble and soluble fractions (bassorin and tragAcanthin, respectively) were studied and it was found that the Smidsrød parameter B, the empirical stiffness parameter was lower than that of several polysaccharides indicating the stiff backbone for tragACanthin.

191 citations


Journal ArticleDOI
TL;DR: Chitin/SF blend nanofibrous matrix, particularly the one that contained 75% chitin and 25% SF, could be a potential candidate for tissue engineering scaffolds because it has both biomimetic three-dimensional structure and an excellent cell attachment and spreading for NHEK and NHEF.

174 citations


Journal ArticleDOI
TL;DR: In this paper, the authors used response surface methodology (RSM) to optimize microencapsulation yield using three independent variables; the ratio of coating material to core material, the emulsifier concentration, and the CaCl2 concentration.

163 citations


Journal ArticleDOI
TL;DR: The degraded and natural porphyrans possessed scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH)-radical activity and reducing power, and indicated that the antioxidant activities were closely related to the molecular weight.

160 citations


Journal ArticleDOI
Tiehong Yang1, Min Jia1, Jia Meng1, Hong Wu1, Qibing Mei1 
TL;DR: The time-effect relation of cytokines response also suggests that macrophages and natural killer cells involved in nonspecific immunity were primary activated, and helper T cell were secondarily affected by AP.

145 citations


Journal ArticleDOI
Yan-Jun Hu1, Yi Liu1, Ting-Quan Sun, Ai-Min Bai, Jian-Quan Lü, Zhen-Bang Pi1 
TL;DR: It was proved that the fluorescence quenching of BSA by Intal is a result of the formation of Intal-BSA complex and the distance R between the donor and acceptor has been obtained.

119 citations


Journal ArticleDOI
TL;DR: This paper describes how the InlB protein was sub-divided into three shorter overlapping peptide fragments yielding truncated functional protein of M(R) 23, 35 and 45 kDa, respectively, which was optimised and confirmed by immobilised metal affinity chromatography (IMAC) and electrophoresis and Western blotting.

96 citations


Journal ArticleDOI
TL;DR: The approach of controlling secondary structure formation of proteins by solvent vapor treatment and monitoring real-time conformational changes may be useful for the design and tailoring of materials for biomedical applications.

95 citations


Journal ArticleDOI
TL;DR: With an increase in both GP concentration and temperature, the gelatin network gradually shifted from being dominated by hydrogen bonds (physical crosslinks) to covalent crosslinking (chemical crosslinks).

89 citations


Journal ArticleDOI
TL;DR: A high molecular weight water-soluble glue protein, sericin was identified in the cocoon peduncle of the tropical tasar silkworm, Antheraea mylitta and Amino acid analysis showed that the protein is enriched in glycine and serine.

Journal ArticleDOI
TL;DR: The interaction between Oxaprozin-E and bovine serum albumin was studied by spectroscopic methods including fluorescence and UV-vis absorption spectroscopy and results indicate the binding reaction was mainly entropy-driven and hydrophobic forces played major role in the binding Reaction.

Journal ArticleDOI
Aline Tirat1, Felix Freuler1, Thomas Stettler1, Lorenz M. Mayr1, Lukas Leder1 
TL;DR: Two novel methods where target proteins can be expressed in E. coli with a fusion partner that allows protein modification in a covalent and highly selective manner are investigated and indicate that these novel site-specific labelling reactions work in a highly efficient manner, allow almost quantitative labelling of the target proteins, have no deleterious effect on the biological activity and are easy to perform in standard laboratories.

Journal ArticleDOI
TL;DR: The thermodynamic parameters indicated that the hydrogen bond and hydrophobic forces played a major role in the interaction of doxepin hydrochloride with BSA.

Journal ArticleDOI
TL;DR: It is noteworthy that S-GAP-P could accelerate the antitumor activity of CTX and improve the immunocompetence damaged by CTX, suggesting the combination might increase cytotoxic efficacy and decrease toxicity of some chemotherapeutic agents in cancer treatment.

Journal ArticleDOI
He-Dong Bian1, Mei Li1, Qing Yu1, Zhen-Feng Chen1, Jianniao Tian1, Hong Liang1 
TL;DR: The decreased binding constant indicates that common ions and UV C irradiation have effect on artemisinin binding to BSA, and the binding mode, the binding constant and the protein structure changes in the presence of art Artemisinin in aqueous solution at pH 7.40 are evaluated.

Journal ArticleDOI
TL;DR: Modification of maize and cassava starches was done using recovered coconut oil and microbial lipase to achieve modified starch with higher DS attributed to the thermostability, since onset of decomposition is at a higher temperature than the unmodified.

Journal ArticleDOI
Yingchao Li1, Lei Dong1, Ai Jia1, Xin-ming Chang1, Hui Xue1 
TL;DR: Stability evaluation showed relatively long-term stability with only slight particle growth after storage at room temperature for 4 weeks, and ultrasonication is demonstrated to be a simple, available and effective method to prepare high quality SLN loaded traditional Chinese medicine.

Journal ArticleDOI
TL;DR: Adsorption isothermal curve indicated that maximal adsorption capacity could be found in the Cu(2+)-CTS-SiO(2) with the value of 4980+/-125 IUg(-1) of the adsorbent, while the maximal adsOrption capacity for trypsin on Zn(2)+ and Ni(2+) loaded adsorbents was 3762+/-68 IUg (-1) and 2636+/-53 IUg -1

Journal ArticleDOI
TL;DR: It was observed that after 10 adsorption-elution cycle, poly(GMA)-Cibacron Blue F3GA beads can be used without significant loss in lysozyme advertisersorption capacity.

Journal ArticleDOI
TL;DR: Data showed that shearing is an important step for increasing orientation and silk II (beta-sheet) structure, and the mechanical properties of the regenerated silk fibers can also be improved by shearing.

Journal ArticleDOI
Wenying He1, Ying Li1, Jianghong Tang1, Feng Luan1, Jing Jin1, Zhide Hu1 
TL;DR: The thermodynamic parameters obtained and the results of spectroscopic measurements suggest that hydrophobic and electrostatic interactions are the predominant intermolecular forces stabilizing two coordination compounds.

Journal ArticleDOI
TL;DR: It was observed that all-trans retinoic acid hydrogen bonded with Trp 214 and Asp 451 residues of subdomain IIA and IIIA of HSA, respectively, suggesting that apart from hydrophobic interactions electrostatic interactions are present.

Journal ArticleDOI
TL;DR: Detailed insight is provided into the binding specificity of the natural alkaloid to single stranded poly(A) over several other single and double stranded nucleic acid structures suggesting its potential as a lead compound for RNA based drug targeting.

Journal ArticleDOI
TL;DR: It is shown that the membrane anchor of YadA from Yersinia enterocolitica is a beta-barrel, but contains a helical part at its N-terminus, and is a trimer of extreme stability.

Journal ArticleDOI
TL;DR: Results suggest that chemisorption processes could be the rate-limiting step in the adsorption process and two kinetic models including pseudo-first order and pseudo-second order model was estimated on the basis of comparative analysis of the corresponding rate parameters, equilibrium capacity and correlation coefficients.

Journal ArticleDOI
TL;DR: Results suggest CS/poloxamer sponges prepared by SIPNs method have good possibility for wound dressing application owing to rapid water adsorption, high mechanical strength, and interconnected cross-sectional morphology of SipNs.

Journal ArticleDOI
TL;DR: Overall, the judicious use of GP to crosslink G was an appropriate means of kinetically trapping MD within the gelatin network.

Journal ArticleDOI
Ping Ding1, Ke-Long Huang1, Gui-yin Li1, Yan-Fei Liu1, Wen-Wen Zeng1 
TL;DR: The kinetic experimental data properly correlated with the second-order kinetic model, which indicates that the chemical adsorption is the rate-limiting step.

Journal ArticleDOI
TL;DR: The antigen binding activity of the antibodies in the various organic solvents increased in the following order: ethanol