F
Franco B. du Preez
Researcher at University of Manchester
Publications - 11
Citations - 376
Franco B. du Preez is an academic researcher from University of Manchester. The author has contributed to research in topics: Ontology (information science) & Annotation. The author has an hindex of 8, co-authored 10 publications receiving 354 citations. Previous affiliations of Franco B. du Preez include VU University Amsterdam & Stellenbosch University.
Papers
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Journal ArticleDOI
RightField: embedding ontology annotation in spreadsheets.
Katy Wolstencroft,Stuart Owen,Matthew Horridge,Olga Krebs,Wolfgang Mueller,Jacky L. Snoep,Franco B. du Preez,Carole Goble +7 more
TL;DR: RightField is an open source application that provides a mechanism for embedding ontology annotation support for Life Science data in Excel spreadsheets, enabling scientists to consistently annotate their data with 'semantic annotation by stealth'.
Journal ArticleDOI
Sustained glycolytic oscillations in individual isolated yeast cells
Anna-Karin Gustavsson,David D. van Niekerk,Caroline B. Adiels,Franco B. du Preez,Mattias Goksör,Jacky L. Snoep,Jacky L. Snoep,Jacky L. Snoep +7 more
TL;DR: This is the first time that sustained limit‐cycle oscillations have been demonstrated in isolated yeast cells, and a detailed kinetic model for the cellular reactions is used, assuming small differences in a single internal parameter.
Book ChapterDOI
The SEEK: a platform for sharing data and models in systems biology.
Katy Wolstencroft,Stuart Owen,Franco B. du Preez,Olga Krebs,Wolfgang Mueller,Carole Goble,Jacky L. Snoep +6 more
TL;DR: The SEEK is promoted as a data and model management tool that can be adapted to the specific needs of a particular systems biology project and the methods employed for lowering the barriers to adoption of standard formats are presented.
Journal ArticleDOI
From steady-state to synchronized yeast glycolytic oscillations I: model construction.
Franco B. du Preez,David D. van Niekerk,Bob W. Kooi,Johann M. Rohwer,Jacky L. Snoep,Jacky L. Snoep,Jacky L. Snoep +6 more
TL;DR: An existing detailed kinetic model for the steady‐state behavior of yeast glycolysis was tested for its ability to simulate dynamic behavior and the model was validated for a wide variety of experiments on oscillatory yeast cells.
Journal ArticleDOI
Glutathione metabolism modeling: A mechanism for liver drug-robustness and a new biomarker strategy
Suzanne Geenen,Franco B. du Preez,Franco B. du Preez,Jacky L. Snoep,Jacky L. Snoep,Jacky L. Snoep,Alison J. Foster,Sunil Sarda,J. Gerry Kenna,Ian D. Wilson,Hans V. Westerhoff +10 more
TL;DR: A robust mathematical model of the dynamics of cellular changes in glutathione homeostasis in cells has been developed and tested in vitro and revealed that a threshold input concentration of methionine may be required for effective detoxification of reactive metabolites by glutATHione conjugation.