F
Franco Borzio
Researcher at University of Milan
Publications - 68
Citations - 4744
Franco Borzio is an academic researcher from University of Milan. The author has contributed to research in topics: Hepatocellular carcinoma & Liver cancer. The author has an hindex of 36, co-authored 68 publications receiving 4084 citations.
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Journal ArticleDOI
Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: a prospective study
Saving Bruno,Enrico Silini,Andrea Crosignani,Franco Borzio,Gioacchino Leandro,Fulvia Bono,M. Asti,Sonia Rossi,Alberto Larghi,Antonella Cerino,Mauro Podda,Mario U. Mondelli +11 more
TL;DR: Cirrhotic patients infected with HCV type 1b carry a significantly higher risk of developing HCC than patients infected by other HCV types, and the latter may require a less intensive clinical surveillance for the early detection of neoplasia.
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Diagnostic and prognostic role of alpha-fetoprotein in hepatocellular carcinoma: both or neither?
Fabio Farinati,Dario Marino,Massimo De Giorgio,Anna Baldan,Maria Chiara Cantarini,Carmela Cursaro,Gianludovico Rapaccini,Paolo Poggio,Maria Anna Di Nolfo,Luisa Benvegnù,Marco Zoli,Franco Borzio,Mauro Bernardi,Franco Trevisani +13 more
TL;DR: The evaluation of this large series of HCC patients allowed us to confirm the low sensitivity of AFP in the diagnosis of H CC and its prognostic value, albeit limited, being tumor size, female sex, Child-Pugh score, and TNM staging independent predictors.
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Semiannual surveillance is superior to annual surveillance for the detection of early hepatocellular carcinoma and patient survival.
V. Santi,Franco Trevisani,Annagiulia Gramenzi,Alice Grignaschi,Federica Mirici-Cappa,Paolo Poggio,Maria Anna Di Nolfo,Luisa Benvegnù,Fabio Farinati,Marco Zoli,Edoardo G. Giannini,Franco Borzio,Eugenio Caturelli,Maria Chiaramonte,Mauro Bernardi +14 more
TL;DR: Semiannual surveillance increases the detection rate of very early hepatocellular carcinomas and reduces the number of advanced tumors as compared to the annual program, which translates into a greater applicability of effective treatments and into a better prognosis.
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Liver cell dysplasia is a major risk factor for hepatocellular carcinoma in cirrhosis: A prospective study
Mauro Borzio,S. Bruno,Massimo Roncalli,Guido Colloredo Mels,Giorgio Ramella,Franco Borzio,Gioacchino Leandro,Ernesto Servida,Mauro Podda +8 more
TL;DR: The results indicate that liver cell dysplasia is a major risk factor for HCC, and it should be looked for carefully by pathologists in liver biopsy specimens to identify patients requiring more intensive observation.
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Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development
Mauro Borzio,Silvia Fargion,Franco Borzio,Anna Ludovica Fracanzani,Anna Maria Croce,Tommaso Stroffolini,Silvia Oldani,Rodolfo Cotichini,Massimo Roncalli +8 more
TL;DR: Macronodules characterize a cirrhotic subpopulation with high risk of hepatocellular carcinoma; HGDN and LCC are strong predictors of malignant transformation; subjects with simultaneous presence of both these two conditions are at highest risk of cancer development.