F
François Lefèvre
Researcher at Institut national de la recherche agronomique
Publications - 156
Citations - 6034
François Lefèvre is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Population & Genetic diversity. The author has an hindex of 42, co-authored 147 publications receiving 5439 citations.
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Journal ArticleDOI
Potential for evolutionary responses to climate change – evidence from tree populations
Florian Alberto,Florian Alberto,Florian Alberto,Sally N. Aitken,Ricardo Alía,Santiago C. González-Martínez,Heikki Hänninen,Antoine Kremer,Antoine Kremer,François Lefèvre,Thomas Lenormand,Sam Yeaman,Ross W. Whetten,Outi Savolainen +13 more
TL;DR: Responding to climate change will likely require that the quantitative traits of populations again match their environments, and it is found that genetic differentiation between populations and clinal variation along environmental gradients were very common.
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A Novel Mucosal Vaccine Based on Live Lactococci Expressing E7 Antigen and IL-12 Induces Systemic and Mucosal Immune Responses and Protects Mice against Human Papillomavirus Type 16-Induced Tumors
Luis G. Bermúdez-Humarán,Naima G. Cortes-Perez,François Lefèvre,Valeria Guimarães,Sylvie Rabot,Juan Manuel Alcocer-González,Jean-Jacques Gratadoux,Cristina Rodríguez-Padilla,Reyes Tamez-Guerra,Gérard Corthier,Alexandra Gruss,Philippe Langella +11 more
TL;DR: The preclinical results suggest the feasibility of the low-cost mucosal vaccination and/or immunotherapy strategies against HPV-related cervical cancer in humans.
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Pre-slaughter conditions, animal stress and welfare: current status and possible future research
E. M. C. Terlouw,Cécile Arnould,B. Auperin,Cécile Berri,E. Le Bihan-Duval,Véronique Deiss,François Lefèvre,B. J. Lensink,L. Mounier +8 more
TL;DR: The present paper describes the main procedures used to slaughter fowl, pigs, calves and adult cattle, sheep, and farmed fish, starting on the farm and ending with the death of the animal at the abattoir, and reviews the currently known causes of stress.
Journal ArticleDOI
Dispersal and gene flow of Populus nigra (Salicaceae) along a dynamic river system
Eric Imbert,François Lefèvre +1 more
TL;DR: The discrepancy between potential gene flow and effective gene flow is interpreted as an effect of fragmentation, due to the alteration of the natural dynamics of the riparian ecosystem rather than to physical barriers.
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Phenotypic plasticity and evolutionary demographic responses to climate change: taking theory out to the field
TL;DR: In this article, the authors review recent theory on the interaction of phenotypic plasticity, genetic evolution and demography in environments that change in time or space, and discuss the main limitations of the models and the difficulties in testing theoretical predictions in the wild.