F
Frank Echtermeyer
Researcher at University of Erlangen-Nuremberg
Publications - 3
Citations - 562
Frank Echtermeyer is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Laminin & Cell migration. The author has an hindex of 3, co-authored 3 publications receiving 544 citations.
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Journal ArticleDOI
Absence of integrin alpha 7 causes a novel form of muscular dystrophy.
Ulrike Mayer,Gesine Saher,Reinhard Fässler,Bornemann A,Frank Echtermeyer,von der Mark H,Nicolai Miosge,Ernst Pöschl,von der Mark K +8 more
TL;DR: Findings demonstrate that αβ1 integrin represents an indispensable linkage between the muscle fibre and the extracellular matrix that is independent of the dystrophin–dystroglycan complex–mediated interaction of the cytoskeleton with the muscle basement membrane.
Journal ArticleDOI
Specific induction of cell motility on laminin by alpha 7 integrin.
TL;DR: Findings prove that α7 integrin expression confers a gain of function-motile phenotype to immobile cells and may be responsible for transduction of the laminin-induced cell motility.
Journal ArticleDOI
The role of extracellular and cytoplasmic splice domains of alpha7-integrin in cell adhesion and migration on laminins.
Stephan Schöber,Dirk Mielenz,Frank Echtermeyer,Sandra Hapke,Ernst Pöschl,Helga von der Mark,Helga Moch,Klaus von der Mark +7 more
TL;DR: It is shown that all three alpha7 splice variants (containing the X2 domain), as well as alpha6A and alpha6B, promote cell attachment and stimulate cell motility on laminin-1 and its E8 fragment, and this results demonstrate selective responses of alpha6- and alpha7-integrins and of the alpha7Splice variants to laminationin- 1 and -2 and indicate differential roles in laminIn-controlled cell adhesion and migration.