Franz Waldhauser

TL;DR: The area under the concentration-time curve for serum melatonin correlated well with the cumulative melatonin excretion during the initial 15 h after melatonin's administration, indicating that either approach can be used to estimate the absorption of orally administered melatonin.

TL;DR: Nocturnal plasma concentrations of luteinising hormone measured at various stages of puberty tended to vary inversely with those of melatonin, and past difficulties in demonstrating a relation between gonadal maturation and human pineal function may have reflected the use of insufficiently sensitive or specific melatonin assays, or serum sampling only during daytime.

TL;DR: It is concluded that melatonin, administered orally in pharmacological quantities, has significant but short acting sedative-like properties.

TL;DR: An acute pharmacological dose of aMT causes isolated elevation of serum PRL levels and may slightly increase GH and Hormones of the pituitary gonadal axis as well as TSH and cortisol are not altered by aMT.

TL;DR: Procedures for screening for congenital adrenal hyperplasia are recommended here in order to provide a structure to the testing and ultimately bring together data that will allow the effect of screening to be judged for benefit or dismissed as no better than clinical recognition of the disease state.