F
Frauke Bataille
Researcher at University of Regensburg
Publications - 63
Citations - 4029
Frauke Bataille is an academic researcher from University of Regensburg. The author has contributed to research in topics: Melanoma & Carcinoma. The author has an hindex of 36, co-authored 63 publications receiving 3760 citations.
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Journal ArticleDOI
Differential Gene Expression of Eph Receptors and Ephrins in Benign Human Tissues and Cancers
Christian Hafner,Gerd Schmitz,Stefanie Meyer,Frauke Bataille,Peter Hau,Thomas Langmann,Wolfgang Dietmaier,Michael Landthaler,Thomas Vogt +8 more
TL;DR: Eph/Ephrin genes are widely expressed in all adult organs with certain organ-site-specific patterns and their function in adult tissues remains unknown, further analysis of their role in disease may disclose new insights beyond their well-defined meaning in development.
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Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma
T. Amann,Frauke Bataille,Thilo Spruss,Marcus Mühlbauer,Erwin Gäbele,Jürgen Schölmerich,P. Kiefer,Anja-Katrin Bosserhoff,Claus Hellerbrand +8 more
TL;DR: It is indicated that stromal HSC promotes HCC progression and the HSC–HCC interaction is suggested as an interesting tumor differentiation‐independent target for therapy of this highly aggressive cancer.
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Expression of Dickkopf genes is strongly reduced in malignant melanoma.
TL;DR: Experimental studies indicate that loss of DKK-3 expression may contribute to melanoma progression, and downregulation of fibronectin, snail-1 and re-expression of E-cadherin was found in the DKR-3 expressing cell clones supporting a role of DKR in tumor progression.
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Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines.
TL;DR: The results suggest that loss of RKIP in malignant melanoma contributes to enhanced invasiveness of transformed cells and therefore to progression of the disease.
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Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model
Sven A. Lang,Andreas Gaumann,Gudrun E. Koehl,Ulrike Seidel,Frauke Bataille,Dagmar Klein,Lee M. Ellis,Ulrich Bolder,Ferdinand Hofstaedter,Hans J. Schlitt,Edward K. Geissler,Oliver Stoeltzing +11 more
TL;DR: In conclusion, mTOR is frequently activated in human gastric cancer and represents a promising new molecular target for therapy.