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Anja K. Bosserhoff
Researcher at University of Erlangen-Nuremberg
Publications - 189
Citations - 8093
Anja K. Bosserhoff is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Melanoma & Gene expression. The author has an hindex of 48, co-authored 189 publications receiving 7288 citations. Previous affiliations of Anja K. Bosserhoff include University of Regensburg & RWTH Aachen University.
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Journal ArticleDOI
Loss of E-cadherin Expression in Melanoma Cells Involves Up-regulation of the Transcriptional Repressor Snail
Ina Poser,David Domı́nguez,Antonio García de Herreros,Alinda Varnai,Reinhard Buettner,Anja K. Bosserhoff +5 more
TL;DR: It is concluded that activation of Snail expression plays an important role in down-regulation of E-cadherin and tumorigenesis of malignant melanomas.
Journal ArticleDOI
Efficient Transfection Method for Primary Cells
TL;DR: The Nucleofector technology developed by amaxa biosystems was able to transfect primary human melanocytes, human coronary smooth muscle cells, human chondrocytes, and human mesenchymal stem cells with high efficiencies, demonstrated by four cell types which are only transfected with low efficiency by other methods.
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miRNA Expression Profiling in Melanocytes and Melanoma Cell Lines Reveals miRNAs Associated with Formation and Progression of Malignant Melanoma
TL;DR: The results of this study not only provide insights into alterations in the miRnomes of melanocytes and melanoma cell lines during melanoma progression but also present a large assortment of miRNAs to be analyzed for their potential as diagnostic markers or targets for therapies in the future.
Journal ArticleDOI
Expression of Dickkopf genes is strongly reduced in malignant melanoma.
TL;DR: Experimental studies indicate that loss of DKK-3 expression may contribute to melanoma progression, and downregulation of fibronectin, snail-1 and re-expression of E-cadherin was found in the DKR-3 expressing cell clones supporting a role of DKR in tumor progression.
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A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease.
Marcus Mühlbauer,Anja K. Bosserhoff,Arndt Hartmann,Wolfgang E. Thasler,Thomas S. Weiss,Hans H Herfarth,Guntram Lock,Jürgen Schölmerich,Claus Hellerbrand +8 more
TL;DR: In Inheritance of the -2518 MCP-1 G allele, which appears to affect hepatic M CP-1 expression, may predispose HCV patients to more severe hepatic inflammation and fibrosis.