Fred Gorstein

TL;DR: Key elements of the consensus are the defining role of KIT immunopositivity in diagnosis and a proposed scheme for estimating metastatic risk in these lesions, based on tumor size and mitotic count, recognizing that it is probably unwise to use the definitive term "benign" for any GIST, at least at the present time.

TL;DR: Key elements of the consensus are the defining role of KIT immunopositivity indiagnosis and a proposed scheme for estimating metastatic risk in these lesions, based on tumor size and mitotic count, recognizing that it is probably unwise to use the definitive term benign for any GIST, at least at the present time.

TL;DR: It is confirmed that progesterone inhibits endometrial stromelysins and the necessity for a stromal-derived factor(s) as a mediator of steroid suppression of an epithelial metalloproteinase is demonstrated.

TL;DR: This article documents major points of agreement and disagreement among experts invited to participate in a Borderline Ovarian Tumor Workshop held in Bethesda, MD, on August 27-28, 2003.

TL;DR: It is suggested that in the absence of a normal progesterone response, common in ectopic lesions of endometriosis, sensitivity to TGF-beta may be altered, resulting in a failure to regulate MMPs.