F
Fulya Cosan
Researcher at Bahçeşehir University
Publications - 29
Citations - 900
Fulya Cosan is an academic researcher from Bahçeşehir University. The author has contributed to research in topics: Familial Mediterranean fever & MEFV. The author has an hindex of 10, co-authored 27 publications receiving 791 citations. Previous affiliations of Fulya Cosan include Kocaeli University & Istanbul University.
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Journal ArticleDOI
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease
Elaine F. Remmers,Fulya Cosan,Yohei Kirino,Michael J. Ombrello,Neslihan Abaci,Colleen Satorius,Julie M. Le,Barbara Yang,Benjamin D. Korman,Aris Cakiris,Oznur Aglar,Zeliha Emrence,Hulya Azakli,Duran Ustek,Ilknur Tugal-Tutkun,Gulsen Akman-Demir,Wei-Wei Chen,Christopher I. Amos,Michael B. Dizon,Afet Akdag Kose,Gülsevim Azizlerli,Burak Erer,Oliver J. Brand,Virginia G. Kaklamani,Phaedon G. Kaklamanis,Eldad Ben-Chetrit,Miles Stanford,Farida Fortune,Marwen Ghabra,William E R Ollier,Young-Hun Cho,Dongsik Bang,John M O'Shea,Graham R. Wallace,Massimo Gadina,Daniel L. Kastner,Ahmet Gül +36 more
TL;DR: The known association of Behçet's disease with HLA-B*51 was confirmed and a second, independent association within the MHC Class I region was identified and the disease-associated IL10 variant was associated with diminished mRNA expression and low protein production.
Journal ArticleDOI
Association of familial Mediterranean fever-related MEFV variations with ankylosing spondylitis.
Fulya Cosan,Duran Ustek,Basar Oku,Julide Duymaz-Tozkir,Aris Cakiris,Neslihan Abaci,Lale Ocal,Orhan Aral,Ahmet Gül +8 more
TL;DR: FMF-related MEFV variations are associated with AS, and these variations may contribute to the pathogenesis of AS, especially in populations in which the prevalence of FMF is high.
Journal ArticleDOI
IL-22-secreting Th22 and IFN-γ-secreting Th17 cells in Behçet's disease
TL;DR: Findings revealed that reduced levels of Tregs and increased levels of Th1 and Th22 cells as well as Th17/Th1 cells might be associated with the pathogenesis of Behçet's disease.
Journal Article
MEFV gene 3'-UTR Alu repeat polymorphisms in patients with familial Mediterranean fever.
Duran Ustek,Cumhur G. Ekmekçi,Basar Oku,Fulya Cosan,Aris Cakiris,Neslihan Abaci,S. Celik,Sevil Kamali,Gulen Hatemi,Ozgur Kasapcopur,H. Ozdogan,Ahmet Gül +11 more
TL;DR: In this article, the 3'-UTR regions of the MEFV gene were investigated in a group of FMF patients with no coding region mutations, to identify variations with a possible role in the regulation of expression.
Journal ArticleDOI
Natural Killer Cell Subsets and Their Functional Activity in Behçet's Disease.
TL;DR: Investigation of the role of NK cell subsets and their cytokine secretion and cytotoxic activity in patients with Behçet’s disease found increases in NK1/NK2 ratio and CD16+IFN-γ+ NK1 cells might support the idea of a biased IFn-γ dominant immune response in the mucocutaneous involvement of BD pathogenesis.