G
Gabriela M. Almeida
Researcher at University of Porto
Publications - 49
Citations - 1855
Gabriela M. Almeida is an academic researcher from University of Porto. The author has contributed to research in topics: Cancer & DNA damage. The author has an hindex of 22, co-authored 47 publications receiving 1609 citations. Previous affiliations of Gabriela M. Almeida include Institute of Molecular Pathology and Immunology of the University of Porto & University of Leicester.
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Journal ArticleDOI
MicroRNA regulation of core apoptosis pathways in cancer
Raquel T. Lima,Sara Busacca,Gabriela M. Almeida,Giovanni Gaudino,Dean A. Fennell,M. Helena Vasconcelos,M. Helena Vasconcelos +6 more
TL;DR: The current knowledge in this area is reviewed, including evidence of miRNA involvement in cancer drug resistance, and many pro-apoptotic miRNAs target anti-APoptotic mRNAs or their positive regulators.
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Biomarkers for gastric cancer: prognostic, predictive or targets of therapy?
Cecília Durães,Gabriela M. Almeida,Raquel Seruca,Raquel Seruca,Carla Oliveira,Carla Oliveira,Fátima Carneiro,Fátima Carneiro +7 more
TL;DR: Clinical approaches based on the combination of correct staging with targeted and conventional systemic therapies may improve gastric cancer patients’ outcome, but are only in their infancy.
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Radiation-induced transgenerational alterations in genome stability and DNA damage
Ruth C. Barber,Peter T. Hickenbotham,T. Hatch,Diane E. Kelly,N. M. Topchiy,Gabriela M. Almeida,George D. D. Jones,George E. Johnson,James M. Parry,Kai Rothkamm,Yuri E. Dubrova +10 more
TL;DR: Transgenerational changes in mutation rates and DNA damage in the germline and somatic tissues of non-exposed first-generation offspring of irradiated inbred male CBA/Ca and BALB/c mice are analysed to provide important clues on the still unknown mechanisms of radiation-induced genomic instability.
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Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells
TL;DR: Curcumin, 3,3′-diindolylmethane (DIM), epigallocatechin gallate (EGCG), genistein, or indole-3-carbinol (I3C) was found to increase cell doubling time as discussed by the authors.
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Wild mushrooms Clitocybe alexandri and Lepista inversa: in vitro antioxidant activity and growth inhibition of human tumour cell lines.
Josiana A. Vaz,Sandrina A. Heleno,Anabela Martins,Gabriela M. Almeida,M. Helena Vasconcelos,M. Helena Vasconcelos,Isabel C.F.R. Ferreira +6 more
TL;DR: The in vitro antioxidant and growth inhibitory activity of extracts obtained from two Portuguese wild mushrooms indicate that these mushrooms are promising sources of bioactive compounds.