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Showing papers in "Food and Chemical Toxicology in 2010"


Journal ArticleDOI
TL;DR: The study suggests that wastewater irrigation led to accumulation of heavy metals in food stuff causing potential health risks to consumers, and heavy metal contamination in the wastewater irrigated site presented a significant threat of negative impact on human health.

728 citations


Journal ArticleDOI
TL;DR: It is suggested that caffeic acid and chlorogenic acid improve body weight, lipid metabolism and obesity-related hormones levels in high-fat fed mice.

645 citations


Journal ArticleDOI
TL;DR: Several monofloral Cuban honeys were analyzed to determine their total phenolic, flavonoid, ascorbic acid, amino acid, protein and carotenoid contents as well as their radical-scavenging activity and antimicrobial capacities.

370 citations


Journal ArticleDOI
TL;DR: The antioxidant properties of lyophilized aqueous extract of propolis (LAEP) from Erzurum province of Turkey is determined and correlated the values with total levels of polyphenolic compounds.

368 citations


Journal ArticleDOI
TL;DR: The results indicate that higher bolus doses of EGCG are hepatotoxic to mice, which is important given the increasing use of green tea dietary supplements, which may deliver much higher plasma and tissue concentrations of E GCG than tea beverages.

344 citations


Journal ArticleDOI
TL;DR: The essential oil composition of myrtle leaf and flower was characterized by high proportions of alpha-pinene, the main compound of monoterpene hydrocarbon class, with 58% for leaf and 17.53% for flower while the stem was rich in oxygenated monoterpenes, largely due to 1,8-cineole.

338 citations


Journal ArticleDOI
TL;DR: It is concluded that tartrazine and carmoisine affect adversely and alter biochemical markers in vital organs e.g. liver and kidney not only at higher doses but also at low doses.

337 citations


Journal ArticleDOI
TL;DR: The present study showed the potential antimicrobial and anticarcinogenic properties of the essential oil of cinnamon bark, indicating the possibilities of its potential use in the formula of natural remedies for the topical treatment of infections and neoplasms.

320 citations


Journal ArticleDOI
TL;DR: The present study aimed to characterize five commercial honeys available in the Portuguese market in respect to their floral origins, physicochemical parameters and microbial safety and commercial quality assessment, and verified that the presence of honey differentially affected the growth of fermentative yeasts under study, depending on the type of yeast.

302 citations


Journal ArticleDOI
TL;DR: Ferulic and caffeic acids have concentration-dependent antioxidant effects in terms of inhibition of lipid peroxidation and reactive oxygen species-scavenging after 2,2'-azobis-amidinopropane dihydrochloride-induced damage in mouse liver microsomes and splenic lymphocytes respectively.

287 citations


Journal ArticleDOI
TL;DR: Results suggest that the use of fucoxanthin may be a useful therapeutic approach for the various inflammatory diseases.

Journal ArticleDOI
TL;DR: It seemed that geographical variation might have influenced the oil compounds either quantitatively or qualitatively as well as qualitative similarities among the oils from different origins.

Journal ArticleDOI
TL;DR: Hepaticum was the most powerful group for the significant decreasing for malondialdehyde and fucosidase activity and some equal improvements were noticed in the histopathological studies for the protective groups.

Journal ArticleDOI
TL;DR: The EOs were found non-mammalian toxic showing high LD(50) for mice (oral, acute) and may be recommended as safe plant based antimicrobials as well as antioxidants for enhancement of shelf life of food commodities by checking their fungal infestation, aflatoxin production as wellAs lipid peroxidation.

Journal ArticleDOI
TL;DR: The potent inhibition of MAO-A by seed and root extracts of P. harmala containing beta-carbolines should contribute to the psychopharmacological and toxicological effects of this plant and could be the basis for its purported antidepressant actions.

Journal ArticleDOI
TL;DR: The results obtained herein strongly indicate that walnut tree constitute an excellent source of effective natural antioxidants and chemopreventive agents.

Journal ArticleDOI
TL;DR: Results suggest that the crude polysaccharide of T.ornata could be considered as a potential antioxidant and anti-inflammatory agent.

Journal ArticleDOI
TL;DR: The presented preconcentration procedure was applied to the determination of metal ions in reference standard materials and some real samples including tap water, spring water, sea water, canned fish, black tea, green tea, tomato sauce and honey.

Journal ArticleDOI
TL;DR: The results indicate that these food colorants had a toxic potential to human lymphocytes in vitro and it seems that they bind directly to DNA.

Journal ArticleDOI
TL;DR: It can be concluded that concomitant administration of quercetin or curcumin with paracetamol may be useful in reversing the toxicity of the drug compared to N-acetylcysteine.

Journal ArticleDOI
TL;DR: Beneficial effects of MFP on hyperlipidaemia rats might be attributed to its dietary fiber, fatty acids, phenolics, flavonoids, anthocyanins, vitamins and trace elements content.


Journal ArticleDOI
TL;DR: Peels polar fractions revealed the highest contents in phenolics, flavonoids, ascorbic acid, carotenoids and reducing sugars, which certainly contribute to the highest antioxidant potential found in these fractions.

Journal ArticleDOI
TL;DR: The results show that olive oil is clearly resistant to frying conditions, independently to the commercial category chosen, and particularly the amount of natural antioxidants are important parameters in their predictive behavior along the frying process.

Journal ArticleDOI
TL;DR: It is shown that piperine at all dosage range used in this study significantly improved memory impairment and neurodegeneration in hippocampus and demonstrated the neurotrophic effect in hippocampus.

Journal ArticleDOI
TL;DR: In this paper, a meta-analysis of response ratios was presented as a possible method of combining and quantifying effects of food processing on pesticide residue levels, which indicated that residue levels were indicated by blanching, boiling, canning, frying, juicing, peeling and washing of fruits and vegetables with an average response ratio ranging from 1 0 to 082.

Journal ArticleDOI
TL;DR: It is suggested that the Bacillus species PSB10 due to its intrinsic abilities of growth promotion and attenuation of the toxic effects of chromium could be exploited for remediation of Chromium from chromium contaminated sites.

Journal ArticleDOI
TL;DR: The results showed that vitamin C might ameliorate imidacloprid-induced oxidative damage by decreasing LPO and altering antioxidant defense system in liver, and the protective effect of the pre-treatment with vitamin C against imidcloprid -induced oxidative stress in liver mice is better than the post-treatment.

Journal ArticleDOI
TL;DR: The water quality in Kohistan region was evaluated by comparing the physio-chemical parameters with permissible limits set by Pakistan environmental protection agency and world health organization and most of the studied parameters were found within their respective permissible limits.

Journal ArticleDOI
TL;DR: Current knowledge suggests phytosterol oxidation products may also cause cytotoxic and pro-apoptotic effects, although at higher concentrations than COPs, which is not clear yet.