G
Gail E. Tomlinson
Researcher at University of Texas Health Science Center at San Antonio
Publications - 187
Citations - 13866
Gail E. Tomlinson is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 57, co-authored 176 publications receiving 12722 citations. Previous affiliations of Gail E. Tomlinson include University of Texas Southwestern Medical Center & University of Texas at Dallas.
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Journal ArticleDOI
Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality
Susan M. Domchek,Tara M. Friebel,Christian F. Singer,D. Gareth Evans,Henry T. Lynch,Claudine Isaacs,Judy Garber,Susan L. Neuhausen,Ellen T. Matloff,Rosalind A. Eeles,Gabriella Pichert,Laura Van T'veer,Nadine Tung,Jeffrey N. Weitzel,Fergus J. Couch,Wendy S. Rubinstein,Wendy S. Rubinstein,Patricia A. Ganz,Mary B. Daly,Olufunmilayo I. Olopade,Gail E. Tomlinson,Joellen M. Schildkraut,Joanne L. Blum,Timothy R. Rebbeck +23 more
TL;DR: Among a cohort of women with BRCa1 and BRCA2 mutations, the use of risk-reducing mastectomy was associated with a lower risk of breast cancer, first diagnosis of breastcancer, all-cause mortality, breast cancer-specific mortality, and ovarian cancer- specific mortality.
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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
Junjie Chen,Daniel P. Silver,Deepika Walpita,Sharon B. Cantor,Adi F. Gazdar,Gail E. Tomlinson,Fergus J. Couch,Barbara L. Weber,Terry Ashley,David M. Livingston,Ralph Scully +10 more
TL;DR: BRCA1 and BRCA2 participate, together, in a pathway(s) associated with the activation of double-strand break repair and/or homologous recombination and Dysfunction of this pathway may be a general phenomenon in the majority of cases of hereditary breast and/ or ovarian cancer.
Journal Article
BRCA2 Is Required for Ionizing Radiation-induced Assembly of Rad51 Complex in Vivo
TL;DR: A requirement of BRCA2 protein for the IR-induced assembly of Rad51 complex in vivo is suggested, suggesting a need for homologous recombination and recombinational repair of DNA double-strand breaks in familial breast cancers.
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Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group
Timothy R. Rebbeck,Tara M. Friebel,Theresa Wagner,Henry T. Lynch,Judy Garber,Mary B. Daly,Claudine Isaacs,Olufunmilayo I. Olopade,Susan L. Neuhausen,Laura van 't Veer,Rosalind A. Eeles,D. Gareth Evans,Gail E. Tomlinson,Ellen T. Matloff,Steven A. Narod,Andrea Eisen,Susan M. Domchek,Katrina Armstrong,Barbara L. Weber +18 more
TL;DR: Short-term HRT use does not negate the protective effect of BPO on subsequent breast cancer risk in BRCA1/2 mutation carriers, and HRT of any type after BPO did not significantly alter the reduction in breast cancerrisk associated with BPO.
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Loss of Heterozygosity for Chromosomes 1p and 16q Is an Adverse Prognostic Factor in Favorable-Histology Wilms Tumor: A Report From the National Wilms Tumor Study Group
Paul E. Grundy,Norman E. Breslow,Sierra M. Li,Elizabeth Penman,J. Bruce Beckwith,Michael L. Ritchey,Robert C. Shamberger,Gerald M. Haase,Giulio J. D'Angio,Milton Donaldson,Max J. Coppes,Marcio H. Malogolowkin,Patricia Shearer,Patrick R.M. Thomas,Roger M. Macklis,Gail E. Tomlinson,Vicki Huff,Daniel M. Green +17 more
TL;DR: Tumor-specific LOH for both chromosomes 1p and 16q identifies a subset of FH Wilms tumor patients who have a significantly increased risk of relapse and death.