Galen P. Miley

TL;DR: A better understanding of iNOS’ complex functions is necessary before specific drug candidates can be identified for classical indications such as sepsis, heart failure, and pain; however, newer promising indications for iN OS inhibition, such as depression, neurodegenerative disorders, and epilepsy, have been discovered.

TL;DR: Regularizing access to fungal secondary metabolite BGCs at an unprecedented scale stands to revitalize drug discovery platforms with renewable sources of natural products.

TL;DR: In this article, the phase-sensitive extreme ultraviolet imaging reflectometer was proposed to measure surface topography, layer thicknesses, and interface quality, as well as dopant concentrations and profiles.

TL;DR: In this paper, the first 13-nm reflection-mode lensless imaging with high-harmonic beam at grazing incidence has been presented, which can image general samples with extreme ultraviolet and soft x-ray light.

TL;DR: A convergent synthesis of tambromycin was achieved by a 13-step route that leveraged recent developments in the field of C-H functionalization to prepare the complex indole fragment, as well as an efficient synthesis ofTambroline that featured a diastereoselective amination of homoproline.